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At WOU, you'll find a variety of room and board options, from residence halls to apartments. Enjoy breakfast, lunch and dinner, too! Recently remodeled Landers Hall is open to first-year students for Fall Western Oregon University has a new logo, new and new fashions. There's new gift merchandise, too.

Check it out! Western Oregon University is breaking new ground again with the Tuition Choice. Save money now or save later - it's your choice. Western's Summer Orientation and Registration program will make your transition to college a positive experience. Snapshots are typically kept for a few weeks and can be used to restore a deleted or overwritten file. Western Oregon University welcomes Tim Wise, one of the most prominent antiracist writers and educators in the United States.

With the Western Undergraduate Exchange program, California and other western state residents are eligible for a substantial reduction in non-resident tuition. Take a look at where you'll be spending time on campus including classrooms, the library and more. A variety of students share why they chose to attend Western Oregon University.

Take a closer look at each of these historical communities. Narrated in English. You know what you like to do. You can do it at WOU! Watch our new campus tour to find out more about Western Oregon University. Take an aerial tour of Western Oregon University. Drone footage recorded June Ackerman Single Room Tour Video. Eclipse Weekend Highlights. Live your passion. Earn an undergraduate or graduate degree in Popular Music at Western.

The university education you've worked for is within reach. Explore WOU's options for funding your future. Highlights from the 23rd Annual Cesar E. Chavez Leadership Conference held at Western. The new student intramural recreation field with artificial turf opens on the northwest side of campus. The Story of the Giant Sequoia. Are you fascinated with trees? Green Dot says you have a right, a choice and the power to stand up against violence.

Wolfie's got a new look and goes through mascot training to officially take over at WOU's homecoming game October 17th. Thinking about a career in criminal justice? Learn about WOU's program from four successful graduates. Hear from co-founders Josh Bedlion and Jonny Herrick. En Solidaridad 2 Spanish Version. A message with students from Western Oregon University.

Audio is in Spanish. Western Oregon University students recognize Dia De Los Muertos on campus with face-painting, a photo memorial and dance. Director of Admissions Rob Findtner explains the basics for applying to Western during a Cappex virtual open house. Music composer Ninsheng Mo shares his experience as an international student in the WOU contemporary music program. Experience the world with these student performances.

Highlights from Cesar E. What is FYE and how does it work? Find out more and hear what students tell us about the program. Comeback chopped down. Wolves fall at Humboldt in the opening game of the season opener. Narrated in Chinese. Highlights from the Cesar E.

Academic Excellence Showcase WOU's Academic Excellence Showcase allows students to demonstrate their research and the campus community to experience the various creative interests of our undergraduate students. Join the Multicultural Student Union as they promote sexual diversity and cultural awareness at Western Oregon University. Discover why WOU is the place to get your undergraduate degree in exercise science.

Rehabilitation Counselor Education Program -- Hear what three graduate students say about the master of science in rehabilitation counseling program at Western. Open Captioned. Western Oregon University now has Oregon's only undergraduate program in the field of Gerontology. Vanessa Sandoval explains why she chose Western to major in Community Health. Learn five more ways you can support WOU students. Listen to their rendition of "I Do.

The Hawaii Club presents it's 9th annual Luau featuring traditional island dancing. Learn how to setup and use your new voicemail system in this tutorial by Thomas Groves. Creating a Sustainable Future: Rob Dietz. Three WOU dance instructors explain why Western is a great place for international students to study dance.

WOU celebrates years of living history in this video featuring Todd Hall archival footage, ghost stories and more. Highlights from Western Oregon University's 9th annual Dr. Martin Luther King Jr. Commemorative Dinner. Find out why this out of state student chose WOU. Instructor: Warren Allen. Interdisciplinary Studies Major. The interdisciplinary studies degree program is flexible, allowing students to select complimentary coursework from different departments and divisions.

Everyone at Western wants to see your hard work pay off as a Computer Science Major. WOU students learn how to set a table, butter bread and more from etiquette expert Mindy Lockard. Gomez Graduate Music Recital These monologues are a collection of coming out stories authored and performed by WOU students, alumni, faculty and staff.

Peter Courtney Naming Ceremony. Butler Kitchenette Room Tour Video. President's Holiday Message Discover why Western Oregon University is the place to be for an undergraduate business degree. Chichester student government students experience the benefits of degree progression at WOU.

Pursue what matters most to you. Get a degree in Criminal Justice at Western. How to sign up for Waitlisting Peter Courtney's Commencement Address. Get your degree in biology from Western and move forward with your dream to become a doctor like Joanne Mayberry.

Learn about SOAR. Western Hemisphere Orchestra featuring jazz trumpeter Cuong Vu. Recorded June 7, Who Is Western Oregon University? ED is a two credit course offered each semester on Technology in Education. A video journal of the WOU Health and Wellness Center, from construction to grand opening, football facilities and exercise science labs.

Looking for some new pick-up lines? Odds are the Dating Doctor knows them all! Captioned and voiced in Portuguese. WOU celebrates Arbor Day on campus with readings at three commemorative trees and the planting of a new hemlock. Directed By Dr. Ike Nail. Visual Communication Design is a course of study focused on graphic design and digital art in the Art Department. Students learn about WOU at the undergraduate reception. Together we engage.

Recorded August Hamersly Library Exhibit Spring Punya Mishra Ph. D, Michigan State explores living at the junction of education, creativity, design and technology. International Students Chinese Version. Meet two of WOU's international students majoring in education and visual communication design. Audio is in Chinese. Produced by CM Hall. Directed by Ted deChatelet. Western Oregon University Class of Graduates of Western Oregon University Class of want to thank you for your support and inspiration during their journey as students.

Mock client interview shown. A brief overview of student life along with information on how to apply to WOU. Find your field. Junior Janvier Alaby posted his best scoring effort of the season with 14 points to lead four players in double figures as the No. The Wolves improved to on the year and in Monmouth. International Night presented by the International Club. Develop creative problem-solving methods while mastering key principles and skills in art and design at WOU.

Meet 2 of WOU's international students from China majoring in education and visual communication design. Betty Komp, D-Ore. Criminal Justice Division Criminal justice is an exciting field with a variety of career opportunities for WOU graduates.

Volleyball Season Highlights As a Theatre major at Western, you get a solid base in acting, directing, technical design and more. President's Alumni Holiday Message A holiday message for Western Oregon University alumni, friends and donors. Visual Communication Design Major. Western Oregon University's th Commencement featured this inspirational speech by graduate student Jennifer Kepka. Learn more about a career in Forensic Anthropology from one of Oregon's leading experts.

Alumni and current student athletes talk about their experience at WOU and the value of scholarship support. Recorded April Hear what students have to say about their experience with the art department. Valuable technology tools and financial aid information for graduate students.

A panel discussion on career, practicum and volunteer opportunities for gerontology students. Psychologist Robert Stanulis talks about Veterans in the classroom and what you need to know. Criminal Justice Career Panel A panel of distinguished guests and WOU graduates discuss career opportunities for criminal justice majors. Betty Komp's Commencement Address. Learning to think, research and write about history is useful in a number of careers.

Learn more about majoring in history at WOU. Freshman center Natalie DeLonge led Western Oregon women's basketball with 14 points and also added eight rebounds, but the Wolves ultimately dropped the non-conference game against nationally ranked California Baptist, , on Saturday December 12, Music: Ryan Little. IT recruiter Tony Seminary on "the biggest mistake that keeps Software Engineer graduates from landing their first job. WOU English majors study literary works and figures of various eras and nationalities and become versed in various theories of criticism.

Directed by Keller Coker. Develop critical policy and thinking skills as a WOU political science major. Wind Ensemble Concert June Highlights from the Wolves' final game of the season against the Jacks of Humboldt State University on November 14, Nationally-known inspirational speaker Will Keim speaks frankly to students during New Student Week Some important tips and information about your first visit to Western Oregon University.

Live on wou. Find out why students are drawn to Western and enjoy the Gerontology program. Criminal Justice MA Program Denise Thew Hackett explains the Rehabilitation and Mental Health Counseling Program's opportunity to receive free counseling from graduate level student counselors. There's more than one reason why you should choose Western Oregon University to get your degree!

Weiss addresses faculty and staff for the academic year. Video provided courtesy of Dixie State University. Renaissance and Baroque Music in Venice. Directed by Dirk Freymuth. Check out this brief introduction to WOU's new interactive campus map, featuring high definition video. The Elite Season. Hear from students on what African American inspires them and why. President's Holiday Outtakes Rex and Susan having fun during this year's recording of the holiday messages.

Honors Student Natalie Wallace. Twilight Track Highlights Wolves kept it close against their Division I opponent for most of the game, eventually fall Kim Poage explains the Rehabilitation and Mental Health Counseling Program and an opportunity to receive free counseling from graduate level student counselors.

Go to wou. You'll find a wide variety of musical tracks within Western's Contemporary Music program. Wolves win another nail biter with a late game defensive stand against the Wildcats of Central Washington on October 17, Relive all the key moments! Go Wolves! The Wolves defend their home turf and continue their unbeaten streak, relying on their stout defense and strong running game to seal a win against South Dakota School of Mines and Technology, on November 7, Honors Student Patricia Derosiers.

This game was the Wolves home opener of the season. Paul Evans Town Hall on Education. Paul Evans leads a town hall discussion on education. Creative Arts: Sculpture Design Sequence. Mary Bucy is an educational technology professor in WOU's information technology graduate program. A view of Western Oregon University from above. Recorded September-October The Cesar E.

Highlights from the Wolves' victories last week against Seattle Pacific, , and Saint Martins, The team records 10 steals and Kadeem Strickland scores 17, going from beyond the arc in the Wolves victory over Corban University on December 11, This is an edited portion of the event. Makana Pundyke Scores twice and breaks defender's ankles in the Wolves' victory over Central Washington University, October 3, Assists from Dana Goularte and Kealakekua Makekau.

Honors Student Brianna Williford. Inclusive City Panel Discussion June WOU finishes first with team points. A show with self illuminating costumes. Richard Woodcock: the story of my life. WOU's College of Education benefactor Richard Woodcock talks about his path to success, his research and his impressions of the new building.

Honors Student K. Ashley Heater. Watch the full race of the WOU men's DMR indoor track team setting a new indoor record and becoming national champions! Western Oregon Winds March Ash Creek Invitational 1 Sept. Highlights from the 1st Ash Creek Invitational cross country meet of This highlight reel features 2 songs from the Rio Nights concert by the American Metropole Orchestra.

Recorded July Take this updated aerial tour of Western Oregon University. Footage originally recorded June Recorded June 16, A new visual communication design lab opens in ITC with iMac's and various 3D software for graphic art students. Topic: Meeting our students where they are. Highlight from the season opener against Central Washington University. Wolves lose New Student Orientation - Will Keim.

Matt Utterback's Commencement Address. Highlights from the Commencement Exercises including student speeches and the keynote address. Community Health Career Talk 1. Part , Part , Part Neuroplasticity with Scott Pengelly. Academic Excellence Showcase Highlights. Find the SOAR schedule, learn more and sign-up at wou. Thinking about getting a M. Learn about sense receptors, transduction, neural processing, color vision and more in this lecture by WOU's Rob Winningham.

Recorded March Sonia Kovalevsky Math Day Sonia Kovalevsky Math Day brings high school girls to campus to explore a career in mathematics. WOU has adopted a decentralized budget management style. Community Health Career Talk 2. Learn how simple it is to become a volunteer.

The pantry is located in the Academic Programs and Support Center building. Enjoy this all sports highlight reel from the season at WOU. Prepared for Wolf Auction. Men's Basketball Recruitment Belief, Determination, Selflessness, Enthusiasm: Discover why you should become a member of the Western Oregon University men's basketball team.

Great things happen when wolves come together. Giving Day is Pay it forward! Western Oregon University offers three licensure programs in undergraduate education. Find out how to succeed at WOU. Counselor and Therapists. Watch last year's event, then join us. Together We Celebrate. Advising Lecture featuring Kerry Kincanon.

Diversity Scholars Recognition Dinner Highlights Highlights form the Diversity Scholars Recognition Dinner. Current Trends in Liberal Education. AES Presidential Plenary. Theme: Eclipses. International Club Beach Trip Interesting facts about artwork recently planted near the Richard Woodcock Education Center. Sheri Malstrom. Olson is graduate of Western Oregon University. Two students explain why they decided to major in the new sustainability degree at Western Oregon University. Recorded on a clear night in Monmouth, Ore.

Highlights from WOU vs. Humboldt State University. Oregon Honors Research. WOU honors students work with the Oregon Women's History Consortium to post research and celebrate the th anniversary of the women's suffrage movement for Oregon This video includes footage of the late Oregon Senator Jackie Roberts.

Missed the celebration? Watch this encore presentation of the Holiday Tree Lighting featuring the parade and interviews with alumni and guests. Brasil Band Featuring Choro Das 3 This remodel was funded by capital building funds from the state of Oregon. The RWEC solar project is compete. Western Oregon Winds June Laff Trax featuring Women's Basketball. Eclipse Lecture 3: Astrophotograper Jon Brewster.

Eclipse Lecture 2: Astronomer Richard Berry. Everything you need to know about solar eclipses from Astronomer Richard Berry, M. Students attending the Criminal Justice Careers Day hear from a panel of professionals. Men's Cross Country Full Race. David Ribich wins title. Concert: Pastime With Good Company Directed by Ike Nail. A Witness for Peace Speaker Tour presentation. Learn more from Marissa McCue '21 and join the fun today! Laff Trax featuring Men's Basketball.

See who the winners are after four rounds of Laff Trax. Tickets at wouwolves. Thank you! Giving Day for Western Oregon University was a huge success. This national presentation by Alzheimer's Association Regional Coordinator Alise Liepnieks was videotaped locally with permission from the Alzheimer's Association.

Holiday Tree Lighting Spot Women's Basketball Preview Youth Immigration and Crime Celtic music from the traditional to the movies and beyond. Community Health Career Talk Panel. Men's Cross Country Championship Highlights. Africian Cultural Night It's the Halloween Spooktacular in downtown Monmouth featuring Wolfie and other trick or treaters.

The Safe Operation of Utility Carts. Video from DVD. Thinking about joining AmeriCorps or the Peace Corps? Community Health Career Talk 3. Wolves Highlight Reel Multicultural Part 3: Japanese Drums. Multicultural Part 1: Poetry. Hear what Head Coach Jim Shaw and several seniors said about it. Multicultural Part 4: Jarana.

Men's Basketball Preview Concert: Passion In Music Faculty Technology Showcase State of the University Highlights. John Knight Twilight Highlights. Great American Band Music WOU is a great place to live! Learn more in this short tour of campus housing. Carol of the Bells by Western Oregon Voices. Warren C. Gill: The Epitome of a Veteran. Warren Gill is one of the U. Western Oregon Symphony Fall Pumpkins, pumpkins and more pumpkins To register go to wou. Public Memory and the Ownership of History.

A social science symposium on the role of history inside and outside academia with independent historian and WOU graduate James Masnov. I Found the Perfect Image! Can I Use It? WOU's Sue Kunda explains copyright, public domain, creative commons and when you can use an image or graphic found online.

How Freedom of the Press is Threatened in Honduras. Commencement Outstanding Students. Further hierarchical clustering analyses including heatmaps will provide insights as to whether timing and dose of specific IM interventions and combinations are associated with larger improved outcomes in the chronic pain cohort. National guidelines advise clinicians to decrease opioids for chronic pain management in favor of nonpharmacological modalities, yet we lack evidence for effective strategies.

We evaluated the effectiveness of the IPT model to decrease opioid use and risk. Veterans were assessed prospectively from baseline to 3 and 6 months for change in opioid dose and risk. An adjusted mixed-effects linear regression showed significant average treatment effects of the IPT and time interaction. This was independent of race, baseline pain severity, opioid use disorder, and other factors. Interdisciplinary models that promote a multimodal approach to pain care, including complementary and integrative health, can lead to sustained reductions in opioid use and risk.

Contact: Raveendhara Bannuru, rbannuru tuftsmedicalcenter. Knee osteoarthritis OA is a major public health problem and a leading cause of long-term pain and disability with substantial health-care costs. No effective medical treatments for the disease currently exist. However, no studies have directly compared mind—body interventions with standard therapies for knee OA using an individual-participant data network meta-analysis approach.

This is the first study to examine the efficacy of mind—body therapies for knee OA using this approach, which estimates relative effects of all treatments against each other. Primary outcomes were pain 0— and function 0— , as measured by the Western Ontario and McMaster Universities Osteoarthritis Index.

We synthesized individual participant data and performed a 2-stage analysis using an extension of multivariable Bayesian hierarchical random effects models for multiple treatment comparisons. Tai Chi was as effective as Exercise mean difference: 0. Yoga achieved pain relief comparable to Exercise For function, Tai Chi was as effective as Exercise 1. Yoga had higher benefits on function compared to Exercise 9.

Mind—body interventions produced beneficial effects similar to those of standard physical therapy and exercise in the treatment of knee OA. Therefore, standardized mind—body interventions should be considered as effective therapeutic options for knee OA, highlighting the importance of holistic well-being of the individuals. Contact: Adam Hanley, adam. This study examined the effect of 3 different adjunctive interventions mindfulness meditation, hypnotic suggestion, and cognitive-behavioral psychoeducation on preoperative pain and anxiety as well as physical function in early recovery following primary TJA.

This was a 3-arm, prospective randomized controlled trial conducted in a university-based orthopedic practice. A brief survey measured pain-at-rest, desire for pain medication, and anxiety immediately before and 15 minutes after the preoperative intervention. Findings from this study suggest that a single minute, mindfulness, or hypnosis intervention immediately reduced preoperative pain intensity, pain unpleasantness, and anxiety in patients preparing for TJA.

Historically, we have found no significant improvement in PROMIS PF scores 6 weeks after TJA, whereas with preoperative mindfulness training, we found clinically and statistically significant improvement in self-reported physical function 6 weeks after surgery. These findings suggest that brief, preoperative mindfulness training may be an effective adjunct that can be easily disseminated in clinical settings, provide immediate preoperative pain and anxiety relief, and may improve postoperative physical functioning.

Isabel Roth 1 , and Joan Engebretson 2. With the co-occurring opioid and chronic pain epidemics bringing focus to the need for nonpharmacological pain management, there is a pressing need to develop and implement Integrative Pain Management IPM models.

IPM brings together professionals who are typically underrepresented in biomedical health-care settings: acupuncturists, mindfulness-based stress reduction teachers, and music therapists, among others. Many of these IPM modalities are not currently covered under health insurance, one of several reasons that garnering administrative buy-in to support hiring and credentialing IPM providers may be challenging. An ethnography was conducted in the spring of at a large urban pediatric hospital in the southern United States where an IPM consult service was being pilot tested.

In the current analysis, we aimed to identify implementation strategies used to overcome barriers to implementation of IPM services. TI data management software. Detailed methods have been reported elsewhere. Of the 6 members of the IPM service, 5 had dual training in both a complementary therapy and a biomedical profession.

Working with development professionals to build philanthropic support for the IPM service was crucial to getting the pilot off the ground. To garner administrative buy-in, clinicians worked with high-profile patients offered complementary therapies to their supervisors, built mentoring relationships, and leveraged their non-IPM clinical work to gather support for IPM.

The current analysis identified implementation strategies that may be tested and replicated in future implementation studies of IPM. Identifying effective implementation strategies will be crucial to future IPM implementation efforts. Contact: Els Peeters, e.

There is an increasing demand for complementary and integrative medicine CIM in adults and children in the Netherlands. In , the first Integrative Medicine Pediatrics Outpatient Clinic was created in a large teaching hospital in the Hague. The integrative approach addressing a wide range of neurological complaints among pediatric patients is transforming health care. The collaboration with CIM therapists by implementation a network of referrals is described. The purpose of this study was 1 to characterize the children and parents making use of the pediatric neurology clinic and 2 to determine the perceived effectiveness of CIM in these children using a referral circuit of CIM therapists.

Caregivers and patients experience with CIM treatments were evaluated. The mean age of the neurology patients was A majority of the families reported benefits from CIM and appreciate the collaboration with the referral circuit. Pediatric neurologists should initiate discussion on CIM helping patients and parents to make informed decisions about using CIM and ameliorating the well-being of these children.

Further studies should address the specific role of CIM in children with neurological disorders. Contact: Dennis Anheyer, d. Increasing demands on teachers and students lead to an increase of distress on both sides. Studies have shown positive effects of mindfulness-based interventions on, for example, executive functioning. The aim of this cluster-randomized trial was to gain more insight in the efficacy of a mindfulness-based training in primary schools. A total of children from 13 primary schools were cluster-randomized either to participate in the program immediately or to wait for half a school year.

Afterward, teachers integrated mindfulness techniques in their daily school routine. Also no significant difference in the health-related quality of life index score was found. However, this difference did not sustain long term. Due to nonsignificant group differences at the other time points measured, it can be concluded that the integration of mindfulness exercises in the classroom does not contribute much to the already existing effects.

However, the compliance of the teachers plays a decisive role. Contact: Tiffany Silliman Cohen, sillimanct email. Nonpharmacological-based pain therapies including massage therapy MT and physical therapy PT are an important component of integrative care models for pediatric cancer patients.

The objective is to integrate MT and PT with standard treatment in order to improve function, reduce pain, and alleviate stress in pediatric cancer patients. In September , a pilot initiative offering MT half a day a week in the outpatient pediatric oncology clinic was implemented.

Through multidisciplinary collaborations particularly with nursing and PT, the certified pediatric MT determined patients who would benefit from both therapies to optimize pain control, muscle strength, balance, and physical functioning. Massage interventions included massage, caregiver education, and instruction on self-massage. Follow-up encounters included assessment of symptoms, reinforcement of techniques, and need for additional support.

I look forward to them. Many of our patients are in clinic for multiple hours … it has been extremely easy to incorporate massage therapy into this structure. This pilot has shown that it is feasible and beneficial to add pediatric MT into an outpatient oncology clinic. Integrating a complementary therapy such as MT with PT can help to improve pain, stress, and tight muscles. In addition, it is well received by patients, families and medical team.

Increased lower extremity muscle cocontraction may contribute to age-related impairments in gait and postural control. Tai Chi TC exercise has been shown to improve balance and reduce falls in older adults; however, the neuromuscular mechanisms underlying these benefits are not well understood. This study evaluated the impact of both long- and short-term TC training on lower limb muscle cocontraction and gait characteristics during both single-task ST and cognitively-distracted dual-task DT overground walking.

Long-term effects of TC training were assessed via cross-sectional comparisons of adult TC-experts average Short-term training impact was assessed by randomly assigning TC-naive adults to a 6-month TC training program or a wait-list usual care UC control. Stride time was calculated from footswitch sensors. CCI was calculated for both walking tasks. Twenty-six TC-experts and 60 TC-naive adults were recruited. Long-term, but not short-term TC training was associated with improved lower extremity neuromuscular coordination.

Contact: Gunes Sevinc, gsevinc mgh. Mindfulness-based interventions have been widely utilized to ameliorate anxiety and stress-related symptoms; however, the neural mechanisms underlying these improvements are still largely unknown. Mindfulness meditation provides a basis for enhanced attentional skills and nonjudgmental awareness of sensory experience. Here, we propose that the changes in these attentional and sensory systems may modify context-based stimulus-response associations, and that these changes may underlie improvements in anxiety and stress-related symptoms following mindfulness-based interventions.

We tested this hypothesis using a well-established contextual fear-learning protocol and a randomized longitudinal study design. Behavioral changes and alterations in neural activation patterns associated with fear learning from pre- to postinterventions were assessed using functional magnetic resonance imaging.

A comparison of self-report measures demonstrated that while both interventions decreased stress levels, MBSR resulted in further improvements in anxiety and emotion regulation. Critically, compared to the SME, MBSR intervention was associated with significant increases in connectivity between the amygdala and primary sensory cortex during fear learning. Moreover, while SME was associated with enhanced BOLD response in superior frontal cortex, MBSR was associated with enhanced activity in posterior insula, as well as in primary visual cortices during associative learning.

These results indicate that mindfulness training may improve anxiety related symptoms predominantly though alterations in context-based stimulus-response associations of the threat-related stimuli. While stress-management education predominantly leads to changes in top-down modulation of threat, MBSR intervention resulted in neuroplastic changes in sensory association areas during associative learning.

Considering that alterations in threat processing have been implicated in the etiology of anxiety and stress-related symptoms, these alterations during associative learning may be a key mechanism through which mindfulness-based interventions alter fear learning and foster stress resilience. Roughly 5 million patients in the United States suffer from paralysis resulting in impaired mobility and communication challenges that significantly impact quality of life.

Through noninvasively decoding user intent in real-time, brain computer interfaces BCIs; devices that establish a direct connection between brains and computers hold the potential to bypass neuromuscular pathways and restore mobility and communication.

One promising approach attempts to decipher motor imagery from the electroencephalogram by recording sensorimotor rhythms, which predictably change in response to real and imagined movements. However, major challenges such as long training times and variable proficiency prevent the widespread clinical adoption of this technology. The dose-dependent response of this effect in the MBSR group suggests the recorded patterns are related to meditation practice, however the strongest patterns of alpha upregulation were observed after BCI training.

Whether this finding is a direct result of mindfulness practice or represents some interaction between meditation and BCI training could be explored by examining the effects of neurofeedback on traditional mindfulness training. The strategy of cultivating meditative states during BCI control through MBSR training could have major clinical implications including better BCI performance, the design of more advanced BCI systems, improved functional health status, and higher quality of life.

Clinical research has shown the benefit of meditation techniques to help reduce symptoms of stress. We explored how expert mediators EMs differ from nonmediators NMs in their response to acute stress. Of the 42 people recruited, 6 subjects were removed due to incomplete data or ineligibility. In total, 16 NM and 20 EM were included in this analysis. Subjects had a median age of 40 20—72 years with 17 females.

EM generally had a lower HR throughout the study EMs demonstrate smaller changes in both subjective and objective measures of stress during and after the TSST. These data support the benefits of meditation to reduce the effects of stress for patients. A secondary analysis was performed to evaluate whether intake of an herbal-mineral supplement that is frequently recommended by integrative medicine providers was associated with categorical shifts in blood pressure BP classification, according to consensus guidelines.

The primary study was designed to prospectively evaluate the safety of the supplement over a 6-month time frame. The investigated supplement contained Rosa centifolia , Boerhaavia diffusa , Dendrogyra cylindrus , Convolvulus pluricaulis , Terminalia arjuna , Tribulus terrestris , Rauwolfia serpentina , Rosa vinca , and magnesium aspartate.

A Wilcoxon signed-rank test was used to evaluate the significance of differences in BP classification between the 3 time points. Mean systolic BP decreased by At the 3-month and 6-month study visits, the percentage of participants categorized as normotensive increased and those categorized as hypertensive decreased compared to baseline. Intake of the herbal-mineral supplement was associated with statistically significant and clinically relevant improvements in BP classification.

These findings may serve to inform health-care providers who recommend this formula to their patients and further justify additional research on the studied formula. Cannabidiol CBD has catapulted to the top of the most-favored cannabinoid charts without data from controlled clinical trials to support its use. This survey was designed to assess who was using CBD-dominant cannabis products, what product type they were using, frequency of use, for what conditions and the perception of its effectiveness.

Patients at 3 integrative medicine clinics and clients of 10 partner dispensaries in San Diego, San Francisco, and Chicago who used CBD-dominant products within the past month were recruited to participate in an institutional review board-approved, anonymous online survey REDCap. A total of surveys were completed from June to May The CBD administration forms used were oral tincture Conditions for which CBD was used were chronic pain The impact of CBD on conditions was rated on a 0 not effective to 10 highly effective scale.

The mean ratings for 36 conditions ranged from 6. Information about CBD was obtained from the internet Despite the fact that information about the use of CBD is not emanating from health-care providers, CBD is being used for a wide range of conditions with self-report of therapeutic benefit as assessed by this 1-time observational survey.

The use of natural health products NHPs is common in North America, with many consumers believing they are safe despite the potential for drug interaction. In the adjusted model, physician inquiry about NHP use was most strongly associated with disclosure by patients odds ratio, 5. Contact: Vincent Minichiello, vincent. Over the course of 2 academic years, a hour mindfulness skills-based curriculum Supportive Training for Residents through Education in Mindfulness was facilitated with resident physicians within the departments of family medicine, pediatrics, anesthesiology, and ophthalmology.

Within 2 months posttraining, residents were invited to participate in a voluntary, semistructured phone interview that was subsequently transcribed and deidentified. A team of 6 reviewers independently read the transcripts, identifying themes, and overarching categories. The reviewers then met to discuss and establish common language regarding these themes. Sixty-nine residents participated in the trainings, and 36 interviews were completed.

Although residents received the same mindfulness training and curriculum, many viewed and internalized the training in unique ways. Some residents referred to mindfulness as a tool to be wielded in certain situations, others viewed it as a way to relax and decompress, a method for self-exploration, or as a lens with which to view the world differently.

Residents reported using mindfulness practices most frequently between patient encounters and prior to entering a patient room. These brief practices included mindful walking, deep breathing, and body scan exercises. Residents found these mindfulness practices helped them better cope with patient-related frustrations, be less distracted and more present with each of their patients, and maintain an awareness of their own stress levels and competing emotions.

Across specialties resident physicians found that a hour mindfulness training was influential in their clinical practices. While their perspectives of mindfulness practice varied, residents commonly agreed that they were able to apply brief mindfulness interventions to support themselves and patients in clinic. We conducted a pilot randomized controlled trial RCT to explore whether mindfulness training MT , alone or in combination with aerobic exercise training AT , may improve cognitive function in individuals at risk of dementia.

Retention rates were These results suggest a possible effect of MT on cognitive function in older individuals at risk of dementia. AT did not improve cognitive function and may require a longer intervention duration to show an effect. These promising findings need to be confirmed in a larger RCT. Contact: Erica Sibinga, esibinga jhmi.

We have found that mindfulness-based stress reduction MBSR for urban youth improves psychological functioning and decreases trauma symptoms. Linear additive modeling was used to compared study arms, accounting for baseline differences. Ninety-seven year-old participants consented and 74 completed baseline data collection and were randomized to MBSR or HT. Given the significant vulnerability of this population and the importance of achieving higher rates of HIV viral suppression to reduce transmission, MBSR remains a promising approach to enhance treatment of HIV-infected youth in effort to end the HIV epidemic.

Contact: Rebecca Wells, rewells wakehealth. Secondary outcomes: changes in disability, self-efficacy, pain catastrophizing, and depression. No adverse events or side effects were reported. Contact: Holger Cramer, h. The aim of this study was to assess the efficacy and safety of a comprehensive mind—body medicine program for lifestyle modification including a fasting period in patients with the metabolic syndrome compared to a standard lifestyle program. One hundred forty-five patients with the metabolic syndrome CLM included an initial 5-day fasting intervention followed by 10 weekly 6-hour group meetings focusing on nutrition, aerobic exercise, mindfulness, yoga, and cognitive restructuring.

Secondary outcomes included anthropometric, laboratory, and self-report measures. Outcomes were assessed at weeks 1 after the fasting week , 12 after the lifestyle programs , and 24 follow-up. Few significant group differences were found at week 12 and No serious adverse events occurred. Fasting induced positive short-term effects in patients with the metabolic syndrome; however, these effects were not maintained in the longer term. Fasting can thus be considered a treatment option for this patient group, although it remains to be investigated whether and how the effects of fasting can be maintained in the longer term.

Contact: Paul G. Werthmann, paul. Viscum album extracts VAE have been intensively investigated preclinically and clinically, particularly with regard to antitumoral activity, immunomodulation, quality of live, survival, and safety. Doctors with high experience in VAE therapy describe treatment regimens and clinically significant outcomes not reported in published studies of VAE.

We asked doctors for cases of VAE therapy in cancer patients which they regarded to show a clinically significant outcome connected to VAE therapy. The recruitment strategy included requests via e-mail lists and meetings as well as contacts from a qualitative study with expert doctors in VAE therapy.

We assessed the cases for relevance clinically significant outcome in comparison with the literature and ran them through a validation process: check for data completeness; triangulation of the data from different sources; reevaluation of crucial diagnostic and follow-up tests; and discussion with experts. A total of cases were recruited; 91 cases were excluded in the assessment process, mainly for relevance and validity; 9 cases were published in peer-reviewed medical journals; and 11 are still being investigated.

Older patient data often were incomplete and made validation impossible. The published case reports cover the tumor sites: skin, pancreas, kidney, ovary, pleura, skull, and lymphatic tissue. VAE was administered subcutaneously, intravenously, and intralesionally.

In some of the cases, unusually high dosages of VAE were used. Outcomes were long-term survival, tumor regression, improvement of quality of life, and reduced side effects from cancer treatment. Significant clinical observations of VAE therapy could be captured, elaborated scientifically, and published as case reports in peer-reviewed medical journals. Our search and elaboration procedure could be a model of how to capture relevant clinical experience.

Contact: Janet Nguyen, jngu uni. Interprofessional communication IPC between health-care practitioners HCP can optimise the safe delivery of patient-centred care. In response to calls from HCP, the Australasian Integrative Medicine Association AIMA established an interdisciplinary working group to develop an IPC Guiding Principles for Letter Writing that included letter templates for medical practitioners, pharmacists, nurses, allied health and complementary medicine practitioners.

Development included stakeholder consultation on the draft document. A mixed-methods study design was used to analyse the results from an online public consultation survey and paper questionnaires from AIMA IPC workshop participants. Quantitative and qualitative data from the 2 datasets were merged utilising the principles of triangulation to identify meta-themes.

The respondents 64 from the public consultation survey and 53 workshop participants were representative of the Australian health-care sectors and the lay community. The key themes relating to IPC were the importance of continuity of care, clarity of communication, professionalism, and ongoing education. Results from the 2 samples were congruent with no significant statistical nor qualitative differences identified.

Feedback from respondents will be used to revise the document prior to AIMA endorsement. The findings highlight the role of formal communication pathways in providing multidisciplinary care that is safe, coordinated, and patient centred, and the need for further IPC training and education. Contact: Mary Koithan, mkoithan arizona. A transformed high-quality health-care system requires that nursing faculty and academic leaders be prepared to transform nursing education to prepare our workforce.

Transforming care requires faculty proficient in developing, implementing, and evaluating curricula based on the concepts and principles of integrative care delivery. L Susan Wieland 1 , and Joel Gagnier 2. Contact: L. Susan Wieland, lswieland gmail. Cochrane systematic reviews are considered the gold standard for evaluating the evidence on interventions. A core component of Cochrane methodology is the Cochrane risk of bias tool RoB 1. In , RoB 1. It is important to evaluate how RoB 2.

RoB 2. We assessed the criteria and rating instructions for each bias domain and considered whether these had changed since RoB 1. Criteria for performance bias and detection bias in unblinded trials have changed. Unblinded trials are no longer automatically rated at high risk of performance bias, but subjective outcomes eg, pain in unblinded trials are now automatically at high risk of detection bias, even if obtained through a blinded assessor.

New RoB 2. According to RoB 2. We question the appropriateness and utility of these judgments, particularly in pragmatic trials, which should not be blinded. We suggest some alternative approaches to assessing the risk of detection bias for these outcomes and propose collaboration to develop recommendations on this topic. Along the lines of the Precision Medicine Model, the purpose of this presentation is to describe the 2-phase content validation process used for a taxonomy of skills learned from mindfulness practice that will allow more targeted interventions to address skill-deficits in defined clinical conditions.

Phase I development utilized 11 subject matter experts SMEs over 5 months. I-CVIs ranged from 0. In the last decade, network meta-analysis NMA has become a well-established knowledge synthesis technique used in systematic reviews SR to compare multiple treatments based on all available direct and indirect evidence. Its extent of use to compare therapies in the realm of complementary medicine CAM intervention has not been assessed. An information specialist executed a multidatabase search, and 2 reviewers performed study selection and data collection.

Information on publication characteristics, diseases studied, interventions compared, reporting transparency, outcomes assessed, and other parameters were extracted from each review. Reviews were published between and , with the majority published between and Dietary supplements A diverse set of conditions was identified, the most common being various forms of cancer Most reviews adequately addressed a majority of the PRISMA NMA extension items; however, there were limitations in indication of an existing review protocol, methods to explore network geometry and related findings , and exploration of risk of bias across studies such as publication bias.

Contact: L Susan Wieland, lswieland gmail. The systematic review evidence for effective mind—body therapies for chronic pain is fragmentary and dissemination of information from existing reviews could be improved. We developed and tested a survey with the CAM Field Advisory Board in and then disseminated a revised and expanded online questionnaire through a range of social media channels in We collected demographics and desires for more information on topics surrounding 6 chronic pain conditions eg, chronic back pain and 12 mind—body therapies eg, mindfulness defined by our funder.

Relevant Cochrane acupuncture reviews were published between and and updates of and reviews are ongoing. There is 1 relevant Cochrane yoga review being updated and 1 at protocol stage. Only 1 relevant Cochrane review exists for mindfulness or for massage. The CAM Field is working with Cochrane review groups to produce or update reviews, developing strategies to disseminate the results of these reviews when completed, and looking at how best to use non-Cochrane evidence in the meantime.

Active stretching targeting connective tissues is integral to mind—body therapies including yoga and Tai Chi. These therapies show promise in relieving musculoskeletal pain, but the biological mechanisms underlying therapeutic effects remain largely unknown.

We have previously studied the impact of active stretching on inflammatory processes in a rat model. Here, we extend this work to a porcine model which closer resembles the human musculoskeletal system. We tested the feasibility of an active stretching paradigm in pigs and report preliminary findings on the impact of stretching on local tissue inflammation by measuring inflammatory lesion size, granulocyte and macrophage infiltration, and systemic inflammatory markers.

Lesion area was measured in situ with calipers and cells harvested and stained with CD, granulocyte, and CD mAbs. Active stretching was well tolerated. On average, S lesions contained fewer granulocytes and macrophages than the NS group. A porcine model shows promise for studying the impact of active stretching on inflammation and musculoskeletal health. Future studies with larger samples and higher stretching doses are warranted. Contact: EunMee Yang, eunmeeyang gmail.

Excessive inflammation in myocardial infarction MI is associated with exacerbated myocardial injury. Attenuating inflammation has been proposed as a potential strategy for improving myocardial repair in MI. In previous studies, electroacupuncture EA has been shown to moderate inflammation and exert beneficial effects in various heart-related conditions, but its efficacy and immune-modulating effects on MI are unclear.

Infarcted rats treated with EA showed decreased levels of myocardial enzymes compared to the nontreated infarcted group: cTnT MI: This study demonstrates that EA can attenuate myocardial injury and inflammation in the postinfarcted heart. The findings also provide new insight about the ability of EA to regulate macrophage polarization in MI. While these findings suggest that acupuncture is cardio-protective, potentially through its immune-modulating effects, more research is needed to better understand the mechanisms and clinical implications of acupuncture for MI.

Contact: Joong Sun Kim, centraline kiom. Mantidis Ootheca MO , described as the ootheca of Hierodula patellifera Serville, , Tenodera angustipennis Saussure, , or Statilia maculate Thunberg, in Korean Herbal Pharmacopoeia, is an important herbal material that has been traditionally used for treating several medical conditions including spermatorrhea and pediatric enuresis in Korea.

We evaluated the effect of MO on testicular injury in mouse after radiation exposure. MO protected testicular morphological changes, such as changes in seminiferous epithelial height after radiation exposure. In addition, the remaining proliferating germ cells were higher in the MO-treated group than in the radiation group. The decrease in the sperm count in epididymis caused by irradiation was counteracted by MO. The present study suggests that MO protects form radiation induced testicular injury via an anti-apoptotic effect and recovery of spermatogenesis.

At present, the clinical treatment of pneumonia is mainly anti-infective and late hormone shock therapy. As a kind of traditional Chinese herbal medicine, Lonicerae japonicae Flos Jinyinhua can effectively reverse the progress of pneumonia and has low toxic side effects.

This study looks at finding its core small molecules and related biological mechanisms. We confirmed the therapeutic effect of Lonicerae japonicae Flos on pneumonia by animal experiments and identified the significant substances by liquid chromatography. Using bioinformatics methods, we carried out target fishing and text mining for these small molecules and clustered and enriched the target proteins related to pneumonia.

We use molecular docking to find the most prominent binding pattern of small molecular ligands to protein receptors. The treatment of rat pneumonia with Lonicerae japonicae Flos has the effect of close to dexamethasone, which can reduce the inflammation of lung tissue. A total of 31 compounds were identified in the aqueous extract, which mapped to pneumonia-associated proteins and enriched 46 pathways.

The core mechanism pathway is Lonicerae japonicae Flos —caffeic acid-coagulation factor 2—neuroactive ligand receptor interaction signaling pathway. Caffeic acid participates in the interaction of neuronal receptor ligands on the plasma membrane by binding to coagulation factor 2 and exerts the therapeutic effect of Lonicerae japonicae Flos on pneumonia. The results have experimental value for further synthesis and exploration, and related research methods can be applied to the exploration of other small molecules of traditional Chinese medicine.

Auricular acupuncture AA is used empirically to manage cardiovascular disorders, including elevated blood pressure BP. However, precise mechanisms underlying its effects remain unclear. The present study evaluated medullary processing during modulation of elevated BP by the AA.

During sham-MAA, the needle was inserted into the same acupoint without subsequent mechanical stimulation. Xilei powder XP is a traditional Chinese medicine for treatment of oral ulcer. Based on the methods of network pharmacology, the authors aim to explore the potential targets and immunoregulatory mechanisms of XP and provide a scientific basis for the further explanation of the mechanism for treating oral ulcer.

The screened proteins were searched in the Universal Protein Database Uniprot for the corresponding gene names, which were matched with the genes related to oral ulcer retrieved from the Comparative Toxicogenomics Database. Moreover, the immunoregulatory signaling pathways of XP treating oral ulcer were screened on Kyoto Encyclopedia of Genes and Genomes KEGG , and the network of molecular-target-pathway was constructed by Cytoscape.

We obtained 52 molecular compounds from XP with 39 targets of treating oral ulcer. By analyzing the enrichment of biological process and KEGG pathways, we can found that mechanism of XP for oral ulcer is related to immune inflammatory, small molecule metabolism, hormone level regulation of hormone and neurotransmitter, by regulating interleukin IL signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, PI3K-Akt signaling pathway, and other inflammatory-related pathways.

Based on the methods of data mining and network pharmacology, the authors aim to explore the medication rules of prescriptions for female urogenital diseases FUDs and provide a scientific basis for the further explanation of the mechanism of prescriptions for FUD.

New prescriptions were extracted by entropy clustering analyzing the literatures of case reports about FUD treated by Traditional Chinese formula. The screened proteins were searched in the Universal Protein Database Uniprot for the corresponding gene names, which were matched with the genes related to FUD retrieved from the Comparative Toxicogenomics Database.

Twenty-one prescriptions were included, containing 54 herbs, herbal targets and 52 disease targets. In the network comprised with those functioning targets, there were signaling pathways associated with hormone response and immune response, namely, oxytocin signaling pathway, ovarian steroidogenesis, estrogen signaling pathway, GnRH signaling pathway, porolactin signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, and so on.

The medication rules of was coordinating heart Yang and kidney Yin on the early stage, and nourishing liver and kidney on the advanced stage. It was affected by complex multitargets and multipathways related with phagosome and NOD-like receptor signaling pathway.

The mechanism of new prescriptions for FUD might be the hormone response and immune response. It was affected by complex multitargets and multipathways related with hypothalamus—pituitary—ovary reproductive axis. Digital gene expression profiling DGE , a next-generation gene sequencing technology, was used to observe the effect of moxa smoke PM10 on the gene expression profile of human lung adenocarcinoma A cells.

The differentially expressed genes DEGs identified after PM10 treatment were screened, and their expression patterns were analyzed by cluster analysis, gene ontology GO function significance enrichment analysis, and pathway significance enrichment analysis.

The DEGs during PM10 intervention in A cells and their biological processes and major signal transduction pathways were screened. The relationship between the DEGs and the A cell cycle and apoptosis was analyzed. Our results demonstrate that moxa smoke PM10 has many types of biological activities and can lead to differentially expressed genes in A cells involved in various biological processes. Moxa smoke PM10 is both positive and harmful to the body, so it is necessary to carry out further research on moxa smoke.

Contact: Soo-Jin Jeong, sjijeong kiom. Pattern identification, also known as syndrome differentiation, is an essential part of diagnosis in Korean medicine KM. The treatment of dementia in KM is based on the pattern identification theory including excess and deficiency syndromes. In addition, Hwangryunhaedok-tang exerts neuropreventive effect on memory impairment by reducing cholinergic system dysfunction in a bilateral common carotid artery occlusion rat model.

Overall, our findings may provide the scientific evidences for application of herbal formulas for the dementia treatment based on the pattern identification theory in KM. BCD has been shown to be effective in the clinical treatment of female infertility. To explore the pharmacodynamic material basis of BCD in the treatment of female infertility based on liquid chromatography—mass spectroscopy LC-MS and molecular docking strategy.

The molecular docking technology was used to verify the relationship between the chemical compounds and common targets of BCD for female infertility, so as to find out the potential pharmacodynamic basis. Based on molecular docking technology, we certified that flavonoids, triterpenoid, and saponins were potential pharmacodynamic material basis of BCD for female infertility. LC-MS and molecular docking strategy can find the potential pharmacodynamic substance basis of BCD for female infertility.

Based on the methods of data mining and network pharmacology, the authors aim to explore the medication rules of prescriptions for uterine fibroids and provide a scientific basis for the further explanation of the mechanism of prescriptions for uterine fibroids. New prescriptions were extracted by entropy clustering analyzing the literatures of case reports about uterine fibroids treated by Traditional Chinese formula. The screened proteins were searched in the Universal Protein Database Uniprot for the corresponding gene names, which were matched with the genes related to uterine fibroids retrieved from the Comparative Toxicogenomics Database.

Moreover, the network of herb-compound-target-signaling pathway was showed by Cytoscape. Sixty-seven prescriptions were included, containing herbs, herbal targets, and 46 disease targets. The mechanism of new prescriptions for uterine fibroids might be the hormone response and immune response.

Based on the methods of network pharmacology, the authors aim to explore the potential targets and endocrine mechanisms of Wuziyanzong Pill WP and provide a scientific basis for the further explanation of the mechanism for treating male infertility. The screened proteins were searched in the Universal Protein Database Uniprot for the corresponding gene names, which were matched with the genes related to male infertility retrieved from the Comparative Toxicogenomics Database.

Moreover, the endocrine signaling pathways of WP treating male infertility were screened on Kyoto Encyclopedia of Genes and Genomes KEGG , and the network of molecular-target-pathway was constructed by Cytoscape. We obtained 58 molecular compounds, targets of WP, and 32 targets of male infertility. The common targets of WP treating male infertility were The P value of protein-protein interactions enrichment is under 1. Among them, 10 KEGG pathways were associated with endocrine action, namely, thyroid hormone signaling pathway, prolactin signaling pathway, estrogen signaling pathway, insulin signaling pathway, progesterone-mediated oocyte maturation, oxytocin signaling pathway, GnRH signaling pathway, and ovarian steroidogenesis, oocyte meiosis.

The endocrine mechanisms of WP treating male infertility is probably concerned with complex signaling pathways, yet specific regulatory mechanisms still need further studies to explore and verify. Loneliness ie, feeling alone and social isolation ie. Yet mitigating these social risk factors is challenging, as few interventions have been effective for both reducing loneliness and increasing social contact. Accumulating evidence suggests that mindfulness interventions can improve social relationship processes.

Less is known about the active mechanisms underlying these improvements. Developing mindfulness-specific skills—namely, 1 monitoring present-moment experiences with 2 an orientation of acceptance—may change the way people perceive and relate toward others.

We predicted that developing openness and acceptance toward present experiences is critical for reducing loneliness and increasing social contact and that removing acceptance skills training from a mindfulness intervention would eliminate these benefits. This study demonstrates the efficacy of a 2-week smartphone-based mindfulness intervention for reducing loneliness and increasing social contact in daily life.

Importantly, developing acceptance toward present-moment experiences is a critical mechanism for mitigating these social risk factors. By fostering equanimity with feelings of loneliness and social disconnect, acceptance skills training may allow loneliness to dissipate and encourage greater engagement with others in daily life.

High-calorie diet, closely related to the occurrence and development of multiple diseases, is an unhealthy status of life. However, there is no effective intervention in clinic. A high-calorie diet model was prepared by 3-week-old rats. A total of 37 substances were identified in the pediatric digestion solution, and target proteins were mapped, 25 of which were associated with a high-calorie diet. Overall, the analysis shows that the highest degree of integration was quercetin and PON1 protein, with the highest enrichment of insulin resistance pathway.

Yinlai Decoction is effective in the treatment of pediatric pneumonia, but its mechanism is not yet clear. Based on the relationship between brain-gut axis and immunity, inflammation, and fever, the mechanism of Yinlai Decoction intervention on brain-gut axis related targets was explored by using multisource database information integration method, which provided targeted guidance for experimental research.

Compare Yinlai Tang target and brain-gut axis target to obtain potential targets of Yinlai Tang intervention in brain-gut axis. There were chemical constituents of Yinlai Decoction, targets of Yinlai Decoction, 99 targets related to brain-gut axis, and 35 potential targets of Yinlai Decoction in interfering with brain-gut axis.

The target of Yinlai Decoction intervention on brain-gut axis mainly concentrates on the enzymes related to brain-gut peptide. Its main functions are immunity, inflammation, and energy metabolism. It can participate in the immune response and oxidative damage of human body. Brain-gut axis target database provides important support for brain-gut axis research. However, the effect of radiotherapy does not seem quite satisfying. Therefore, how to increase radiosensitivity is an important topic.

In this study, we analyzed Fuzheng Zengxiao Decoction with the method of network pharmacology, in order to explore the potential targets and mechanism of Fuzheng Zengxiao Decoction in increasing radiosensitivity of NSCLC and provide targeted guidance for the following study. The intervening of a complex multiple-target points pathway may account for the effect of Fuzheng Zengxiao Decoction in increasing radiosensitivity of NSCLC. This study not only makes a contribution to a better understanding of the mechanism of Fuzheng Zengxiao Decoction in increasing radiosensitivity of NSCLC but also proposes a strategy to develop new TCM candidates at a network pharmacology level.

Nonerosive reflux diseases NERD is a type of chronic digestive disorder with a high morbidity in the clinical; however, its therapy remains a great challenge due to the lack of effective drugs. The pathological changes of esophageal mucosa, expansion of esophageal squamous cell space, expression of tryptase, and degranulation of mast cells in esophagus were investigated by different techniques.

The serum levels of esophageal visceral hypersensitivity-related neuropeptides were measured using enzyme-linked immunosorbent assay. In addition, the gene and protein expressions of transient receptor potential vanilloid 1 TRPV1 and transient receptor potential cation channel subfamily M member 8 TRPM8 in esophageal and dorsal root ganglia were investigated, respectively.

This study provides meaningful guidance for treatment of NERD in the clinic. Contact: Changyong Luo, The compounds were searched by PubChem. The drug targets were predicted on the Swiss Target Prediction website. The key genes and pathways in the common target network of ShenfuTang and Shengmaiyin Intervention in septic shock were mainly related to inflammatory reaction and neuro-endocrine-immune system.

The specific target of Shenfutang was mainly related to adrenaline and its insulin secretion. ShenfuTang and Shengmaiyin can treat septic shock through common targets. The unique targets are also focused on the treatment. Yinqiao-san formula YQS , a classic herbal formula, has been widely used to treat pediatric acute respiratory Infection in clinical practice in China. However, the pharmacological mechanisms of YQS still remain unknown.

Furthermore, the major hubs were imported to the KEGG resources to perform pathway enrichment analysis. A total of 91 nodes putative targets were picked out as major hubs in terms of their topological importance. YQS could alleviate pediatric acute respiratory infection through the molecular mechanisms predicted by network pharmacology, and this research demonstrates that the network pharmacology approach can be an effective tool to reveal the mechanisms of traditional Chinese medicine from a holistic perspective.

Acupuncture is suggested as a promising adjunctive therapy to improve the cognitive impairment of individuals with chronic cerebral hypoperfusion CCH. However, the molecular and cellular mechanisms in white matter remain elusive. CCH-induced white matter lesion rats were established by bilateral common carotid arteries occlusion and received a 2-week acupuncture treatment at Zusanli ST36 and Baihu GV Arterial spin labeling and functional magnetic resonance imaging were used for detection of cerebral blood flow and observation of functional connectivity.

White matter integrity was studied by diffusion tensor imaging DTI and immunohistochemistry. Inflammation markers including glia cells, MMP-2, and MMP-9 were detected by immunofluorescence, western blot, and real time polymerase chain reaction. Eight-arm maze was used for assessing of working memory. Acupuncture significantly increased the cerebral blood flow in CC DTI parameters revealed that fractional anisotropy and axial diffusivity of CC were remarkably improved by acupuncture, followed by a significantly attenuation of myelin loss and neural inflammation in white matter.

The purpose of this research was to measure the antioxidant capacity of 6 mushroom species including Ganoderma sp. Both aqueous and hydro-alcoholic extracts of all 6 mushroom varieties where prepared, utilizing a laboratory-based aqueous extraction technique versus a traditional hydro-alcoholic tincturing process. Among the samples tested, chaga and maitake consistently demonstrated higher antioxidant activity, irrespective of the type of assay employed, with ORAC values measuring more than 10 times that of the remaining 4 mushrooms 0.

Mushroom extracts exhibited variable antioxidant capacities depending on species and extraction method. This work evidenced the need to further explore bioactive components of chaga and maitake and how they differ by solvent. A simple aqueous extraction method uniformly resulted in superior antioxidant activity.

These findings could have implications for the herbal medicine community and natural products industry at large. Contact: Yuxiang Wan, wanyuxiang bucm. Hepatocellular carcinoma HCC is one of the most common and fatal cancer globally. Because of its high lethality rate and low 5-year survival rate, HCC poses a severe threat to human health. Even though it has been accepted by the CSCO guidelines for liver cancer, the mechanisms are not yet clearly understood.

Huai er could treat the HCC through the molecular mechanisms predicted by network pharmacology. This study proposes a strategy to explore the underlying mechanisms of TCM at the level of network pharmacology. The aim is to observe the effect of moxibustion on hyperhomocysteinemia and to explore the effect of early intervention of moxibustion on prevention and treatment of atherosclerosis from the angle of enhancing antioxidant capacity and protecting vascular endothelium.

Moxibustion group: mice were grabbed and placed in the fixator to fix the head, tail, and limbs of mice. The moxa sticks were set under the chest of the mice so that the heat was transmitted to the midpoint of the chest of the mice through the small holes at the bottom of the fixator. In the process of moxibustion, the height of moxibustion stick is constantly adjusted to keep the temperature of moxibustion basically constant.

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How to sign up for Waitlisting Peter Courtney's Commencement Address. Get your degree in biology from Western and move forward with your dream to become a doctor like Joanne Mayberry. Learn about SOAR. Western Hemisphere Orchestra featuring jazz trumpeter Cuong Vu. Recorded June 7, Who Is Western Oregon University?

ED is a two credit course offered each semester on Technology in Education. A video journal of the WOU Health and Wellness Center, from construction to grand opening, football facilities and exercise science labs. Looking for some new pick-up lines? Odds are the Dating Doctor knows them all! Captioned and voiced in Portuguese. WOU celebrates Arbor Day on campus with readings at three commemorative trees and the planting of a new hemlock. Directed By Dr. Ike Nail.

Visual Communication Design is a course of study focused on graphic design and digital art in the Art Department. Students learn about WOU at the undergraduate reception. Together we engage. Recorded August Hamersly Library Exhibit Spring Punya Mishra Ph. D, Michigan State explores living at the junction of education, creativity, design and technology. International Students Chinese Version. Meet two of WOU's international students majoring in education and visual communication design.

Audio is in Chinese. Produced by CM Hall. Directed by Ted deChatelet. Western Oregon University Class of Graduates of Western Oregon University Class of want to thank you for your support and inspiration during their journey as students. Mock client interview shown. A brief overview of student life along with information on how to apply to WOU. Find your field. Junior Janvier Alaby posted his best scoring effort of the season with 14 points to lead four players in double figures as the No.

The Wolves improved to on the year and in Monmouth. International Night presented by the International Club. Develop creative problem-solving methods while mastering key principles and skills in art and design at WOU. Meet 2 of WOU's international students from China majoring in education and visual communication design. Betty Komp, D-Ore. Criminal Justice Division Criminal justice is an exciting field with a variety of career opportunities for WOU graduates.

Volleyball Season Highlights As a Theatre major at Western, you get a solid base in acting, directing, technical design and more. President's Alumni Holiday Message A holiday message for Western Oregon University alumni, friends and donors. Visual Communication Design Major. Western Oregon University's th Commencement featured this inspirational speech by graduate student Jennifer Kepka.

Learn more about a career in Forensic Anthropology from one of Oregon's leading experts. Alumni and current student athletes talk about their experience at WOU and the value of scholarship support. Recorded April Hear what students have to say about their experience with the art department.

Valuable technology tools and financial aid information for graduate students. A panel discussion on career, practicum and volunteer opportunities for gerontology students. Psychologist Robert Stanulis talks about Veterans in the classroom and what you need to know. Criminal Justice Career Panel A panel of distinguished guests and WOU graduates discuss career opportunities for criminal justice majors.

Betty Komp's Commencement Address. Learning to think, research and write about history is useful in a number of careers. Learn more about majoring in history at WOU. Freshman center Natalie DeLonge led Western Oregon women's basketball with 14 points and also added eight rebounds, but the Wolves ultimately dropped the non-conference game against nationally ranked California Baptist, , on Saturday December 12, Music: Ryan Little.

IT recruiter Tony Seminary on "the biggest mistake that keeps Software Engineer graduates from landing their first job. WOU English majors study literary works and figures of various eras and nationalities and become versed in various theories of criticism. Directed by Keller Coker. Develop critical policy and thinking skills as a WOU political science major. Wind Ensemble Concert June Highlights from the Wolves' final game of the season against the Jacks of Humboldt State University on November 14, Nationally-known inspirational speaker Will Keim speaks frankly to students during New Student Week Some important tips and information about your first visit to Western Oregon University.

Live on wou. Find out why students are drawn to Western and enjoy the Gerontology program. Criminal Justice MA Program Denise Thew Hackett explains the Rehabilitation and Mental Health Counseling Program's opportunity to receive free counseling from graduate level student counselors. There's more than one reason why you should choose Western Oregon University to get your degree! Weiss addresses faculty and staff for the academic year. Video provided courtesy of Dixie State University.

Renaissance and Baroque Music in Venice. Directed by Dirk Freymuth. Check out this brief introduction to WOU's new interactive campus map, featuring high definition video. The Elite Season. Hear from students on what African American inspires them and why. President's Holiday Outtakes Rex and Susan having fun during this year's recording of the holiday messages.

Honors Student Natalie Wallace. Twilight Track Highlights Wolves kept it close against their Division I opponent for most of the game, eventually fall Kim Poage explains the Rehabilitation and Mental Health Counseling Program and an opportunity to receive free counseling from graduate level student counselors.

Go to wou. You'll find a wide variety of musical tracks within Western's Contemporary Music program. Wolves win another nail biter with a late game defensive stand against the Wildcats of Central Washington on October 17, Relive all the key moments! Go Wolves! The Wolves defend their home turf and continue their unbeaten streak, relying on their stout defense and strong running game to seal a win against South Dakota School of Mines and Technology, on November 7, Honors Student Patricia Derosiers.

This game was the Wolves home opener of the season. Paul Evans Town Hall on Education. Paul Evans leads a town hall discussion on education. Creative Arts: Sculpture Design Sequence. Mary Bucy is an educational technology professor in WOU's information technology graduate program.

A view of Western Oregon University from above. Recorded September-October The Cesar E. Highlights from the Wolves' victories last week against Seattle Pacific, , and Saint Martins, The team records 10 steals and Kadeem Strickland scores 17, going from beyond the arc in the Wolves victory over Corban University on December 11, This is an edited portion of the event. Makana Pundyke Scores twice and breaks defender's ankles in the Wolves' victory over Central Washington University, October 3, Assists from Dana Goularte and Kealakekua Makekau.

Honors Student Brianna Williford. Inclusive City Panel Discussion June WOU finishes first with team points. A show with self illuminating costumes. Richard Woodcock: the story of my life. WOU's College of Education benefactor Richard Woodcock talks about his path to success, his research and his impressions of the new building. Honors Student K. Ashley Heater. Watch the full race of the WOU men's DMR indoor track team setting a new indoor record and becoming national champions!

Western Oregon Winds March Ash Creek Invitational 1 Sept. Highlights from the 1st Ash Creek Invitational cross country meet of This highlight reel features 2 songs from the Rio Nights concert by the American Metropole Orchestra. Recorded July Take this updated aerial tour of Western Oregon University. Footage originally recorded June Recorded June 16, A new visual communication design lab opens in ITC with iMac's and various 3D software for graphic art students.

Topic: Meeting our students where they are. Highlight from the season opener against Central Washington University. Wolves lose New Student Orientation - Will Keim. Matt Utterback's Commencement Address. Highlights from the Commencement Exercises including student speeches and the keynote address.

Community Health Career Talk 1. Part , Part , Part Neuroplasticity with Scott Pengelly. Academic Excellence Showcase Highlights. Find the SOAR schedule, learn more and sign-up at wou. Thinking about getting a M. Learn about sense receptors, transduction, neural processing, color vision and more in this lecture by WOU's Rob Winningham.

Recorded March Sonia Kovalevsky Math Day Sonia Kovalevsky Math Day brings high school girls to campus to explore a career in mathematics. WOU has adopted a decentralized budget management style. Community Health Career Talk 2. Learn how simple it is to become a volunteer.

The pantry is located in the Academic Programs and Support Center building. Enjoy this all sports highlight reel from the season at WOU. Prepared for Wolf Auction. Men's Basketball Recruitment Belief, Determination, Selflessness, Enthusiasm: Discover why you should become a member of the Western Oregon University men's basketball team. Great things happen when wolves come together.

Giving Day is Pay it forward! Western Oregon University offers three licensure programs in undergraduate education. Find out how to succeed at WOU. Counselor and Therapists. Watch last year's event, then join us. Together We Celebrate. Advising Lecture featuring Kerry Kincanon. Diversity Scholars Recognition Dinner Highlights Highlights form the Diversity Scholars Recognition Dinner. Current Trends in Liberal Education. AES Presidential Plenary. Theme: Eclipses.

International Club Beach Trip Interesting facts about artwork recently planted near the Richard Woodcock Education Center. Sheri Malstrom. Olson is graduate of Western Oregon University. Two students explain why they decided to major in the new sustainability degree at Western Oregon University. Recorded on a clear night in Monmouth, Ore. Highlights from WOU vs. Humboldt State University. Oregon Honors Research. WOU honors students work with the Oregon Women's History Consortium to post research and celebrate the th anniversary of the women's suffrage movement for Oregon This video includes footage of the late Oregon Senator Jackie Roberts.

Missed the celebration? Watch this encore presentation of the Holiday Tree Lighting featuring the parade and interviews with alumni and guests. Brasil Band Featuring Choro Das 3 This remodel was funded by capital building funds from the state of Oregon. The RWEC solar project is compete. Western Oregon Winds June Laff Trax featuring Women's Basketball. Eclipse Lecture 3: Astrophotograper Jon Brewster. Eclipse Lecture 2: Astronomer Richard Berry.

Everything you need to know about solar eclipses from Astronomer Richard Berry, M. Students attending the Criminal Justice Careers Day hear from a panel of professionals. Men's Cross Country Full Race. David Ribich wins title. Concert: Pastime With Good Company Directed by Ike Nail. A Witness for Peace Speaker Tour presentation.

Learn more from Marissa McCue '21 and join the fun today! Laff Trax featuring Men's Basketball. See who the winners are after four rounds of Laff Trax. Tickets at wouwolves. Thank you! Giving Day for Western Oregon University was a huge success. This national presentation by Alzheimer's Association Regional Coordinator Alise Liepnieks was videotaped locally with permission from the Alzheimer's Association.

Holiday Tree Lighting Spot Women's Basketball Preview Youth Immigration and Crime Celtic music from the traditional to the movies and beyond. Community Health Career Talk Panel. Men's Cross Country Championship Highlights. Africian Cultural Night It's the Halloween Spooktacular in downtown Monmouth featuring Wolfie and other trick or treaters.

The Safe Operation of Utility Carts. Video from DVD. Thinking about joining AmeriCorps or the Peace Corps? Community Health Career Talk 3. Wolves Highlight Reel Multicultural Part 3: Japanese Drums. Multicultural Part 1: Poetry. Hear what Head Coach Jim Shaw and several seniors said about it. Multicultural Part 4: Jarana. Men's Basketball Preview Concert: Passion In Music Faculty Technology Showcase State of the University Highlights.

John Knight Twilight Highlights. Great American Band Music WOU is a great place to live! Learn more in this short tour of campus housing. Carol of the Bells by Western Oregon Voices. Warren C. Gill: The Epitome of a Veteran. Warren Gill is one of the U. Western Oregon Symphony Fall Pumpkins, pumpkins and more pumpkins To register go to wou.

Public Memory and the Ownership of History. A social science symposium on the role of history inside and outside academia with independent historian and WOU graduate James Masnov. I Found the Perfect Image! Can I Use It? WOU's Sue Kunda explains copyright, public domain, creative commons and when you can use an image or graphic found online. How Freedom of the Press is Threatened in Honduras.

Commencement Outstanding Students. Three outstanding students speak at Commencement Scholarship Application Site Demo. A quick tutorial for WOU admitted students on how to apply for Western scholarships. Learn more about Western Oregon University offering classes in Salem. Multicultural Part 5: Zapateado. Enroll today in a 4-year degree completion program at WOU Salem.

In their last-ever meeting, the Wolves deliver a Homecoming win over Humboldt State. Community Health Career Talk 4. Concert: Music You Want to Hear. Of note: This video, including the audio track, was produced on a sunny day in January during one class period. Visiting Scholar Dance Performance.

Carol of the Bells short version. Community Health Career Talk 5. WOU is graduating champions. Support our student-athletes at wouwolves. A Shoffner Media Production. Deciphering the Elections. Oregon Senator Dembrow on Climate Change. Senator Michael Dembrow speaks to Emily Plec's environmental communication class about climate change and what he's been doing about carbon pricing, renewable energy, emissions and other Oregon issues.

WOU students and faculty share their research projects and explain the benefits of undergraduate research opportunities. Criminal Justice Overview West of Us Concert March Giving Day Staff, Faculty, Alumni v. Creating a Sustainable Future: Aaron Wolf. Western Oregon Symphony March A Choral Fantasy Part 1 Summer Biomass Research Internship. This student video was produced by sustainability major Beryln Buncal.

Posted October Oregon Dept. Four Days in Clint: Firsthand account of a Texas border patrol facility by law professor and child advocate Warren Binford. Congratulations to our winner Caitlyn Healy! Woodburn High School Mariachi. A panel discussion of Free Speech on Campus covering controversial speakers, university preparedness and legal consideration.

This version follows a female Hamlet, played by WOU alum Janelle Rae, who returns home from university to find her life in chaos. Wolf Auction Athletic Highlights. Highlights from the Wolves athletic season presented at the Wolf Auction. Craig Klugman of DePaul University explores our troubled past of human research and medical experiments. A Choral Fantasy Part 2 Geology of the Little Luckiamute Falls.

Western Oregon Winds Dec. Happy Holidays from Western Voices. A series of short presentations about black historical figures, groups and movements sponsored by the WOU Black Student Union. It features three student presentations on strategies used to improve access to food and promote healthy communities.

Here's your point admitted freshman and transfer student checklist. Western Oregon Symphony June WOU students share their most memorable experiences of the academic year. Criminal Justice Career Fair Here's a chance to view WOU's future space in Salem. RC Transition Services in Rehabilitation. Transition Network Facilitator Eivind-Erik Sorensen talks about Oregon's Transition Technical Network supporting secondary students and young adults who experience differing abilities.

Experience WOU Giving Day with call center students, the kickoff choir, data entry workers and those who gave. Thank you to all! A special message to WOU scholarship donors. Natural Science Grand Re-Opening. Two years in the making, the Natural Science building modernization is complete.

RC Vocational Rehabilitation Process. Tyrell Williams Offensive Skills Camp. Due to some inaudible audience comments, portions of this event were edited. Two WOU alumni discuss job hunting after graduation. This video features Emily Geraci and Dave Crockett.

Crow's Shadow Institute of the Arts. History Research on Vick Building. Professor Kim Jensen's Introduction to Public History class conducts research for the Vick building centenary Freebie Fridays is back for winter term See what's coming up for Jan. Football rolls to third straight win with victory over Simon Fraser at home.

WOU football piles up over yards, controls clock and dominates Midwestern State in victory at home. This video includes interpretors. See link for slide presentation. RC Taboo Topics in Counseling. Wolves push 12 Lions to the limit in exciting WOU home opener. WouTV highlights of the Wolves wild overtime game vs the Wildcats featuring 83 combined points. Seniors push for comeback but Eastern New Mexico hangs on to win WOU students discuss how receiving a scholarship to attend Western has changed their lives.

These diverse studio interviews were recorded for Giving Day Contact us today at wou. Creating a Sustainable Future: Philip Harding. Basketball Season Tickets Congress to Campus Public Forum. Criminal Justice Career Day Find out why you should attend the next one.

Congress to Campus Panel Discussion. WOU's Dalven Brushier stamped his name in the school record books helping the Western Oregon men's basketball team to a historic win over the Saint Martin's Saints. EarlyBirdy is a novel tool that can potentially promote sleep hygiene among millennials.

Its unique method for reducing blue light exposure while preventing snoozing has been shown to be feasible. Contact: Allison Carroll, acarroll nm. Purpose: Cardiac surgery patients suffer high rates of depression, somatic sequelae, and medical complications eg, atrial fibrillation.

Although acupuncture is an effective treatment for these conditions, no trials have tested acupuncture among cardiac surgery patients. It is unknown whether cardiac surgery patients would be receptive to acupuncture. Methods: These data are part of a randomized, controlled, feasibility trial of daily acupuncture ACU or treatment as usual TAU following isolated valve surgery via sternotomy.

ACU patients received up to 6 acupuncture sessions during hospitalization. TAU patients had no intervention. Before randomization, all patients reported history of and expectations for acupuncture. At follow-up 3-months postsurgery , ACU patients reported their experience of postoperative acupuncture. During hospitalization, ACU patients underwent 3.

Conclusion: One in 4 cardiac surgery patients had previous, limited experience with acupuncture. Most patients had moderate expectations that acupuncture would benefit them. Nonetheless, the majority of patients who received acupuncture during postoperative hospitalization found acupuncture to be helpful. Future analyses will assess the impact of acupuncture on depressive symptoms, somatic sequelae, and atrial fibrillation.

Contact: Stephen Maris, smaris springfieldcollege. Patients with chronic obstructive pulmonary disease COPD often lose improvements in exercise capacity and health-related quality-of-life after pulmonary rehabilitation PR when exercise is not maintained. In the context of a randomized controlled trial, the goals of this analysis were to 1 explore longitudinal changes in respiratory function after a week post-PR Tai Chi TC intervention and 2 characterize acute cardiorespiratory response to TC versus walking WLK.

Continuous heart rate data during in-class testing was analyzed for conventional heart rate variability HRV indices. Questionnaires assessed quality-of-life, physical function, and dyspnea. There were trends in increased HRV in both time and frequency domains in the recovery phase after TC. Contact: Maria T Chao, maria. First-line treatment for painful diabetic neuropathy PDN consists of analgesic medications with limited efficacy and significant side effects.

Acupuncture is a proven treatment for chronic pain and is a promising emerging alternative. Semistructured interviews were conducted with a subsample of participants from a randomized clinical trial of a group acupuncture intervention for PDN. Interview transcripts were analyzed using an inductive thematic framework. We conducted 27 in-depth qualitative interviews. Participants identified that PDN added significant suffering and disability to the multiple challenges of poverty they were already facing, including housing instability, lack of transportation, and limited access to healthy food.

In general, they found acupuncture not only alleviated many different types of neuropathic pain burning or aching, sensations of heat or cold, numbness but also reduced their reliance on medication. They noted improvements in sleep, stress management, and mood. Some found that they grew more engaged in caring for their diabetes through study participation. They strengthened their understanding of diabetes and PDN as well as their awareness of its effect on well-being.

Finding a beneficial treatment also renewed their hope and motivation. Diverse safety net participants with PDN found group acupuncture helpful in treating their pain and improving overall well-being. More research is warranted to explore the ways in which acupuncture or other complementary therapies could bolster patient empowerment to improve health outcomes in marginalized populations. To determine whether integrative medicine involvement can reduce hospitalization frequency and duration for patients with complex medical conditions and frequent hospitalizations.

Recently, a smaller clinic was established in partnership with the UCLA Extensivist Program to provide high touch care for high utilizers of health care, as defined by at least 2 hospitalizations in the past year; 29 patients had 6-month follow-up data available and were included in this analysis. We used the Epic electronic medical record to determine the total number of hospitalizations and hospitalization days for the year preceding their initial visit.

These patients were then followed for 6 months by integrative east-west medicine physicians. The number of hospitalizations and hospitalization days were determined at 6 months postenrollment and normalized to 1 year. One and 2-tailed paired t tests were used for statistical analyses. Patients had an average of 3. After 6 months of treatment, patients had an average of 1. Integrative medicine specialty care was effective in reducing hospitalization frequency and total hospitalization days among high utilizers of care.

This supports further exploration into using integrative medicine as a cost saving measure among the sickest and most complex patients in the health-care system. Culinary medicine education has become increasingly popular at medical schools across the United States. Medical students electing to participate in experiential culinary medicine education have demonstrated improvements in nutrition knowledge, skills, and attitudes for both self-care and patient care. However, data on the effectiveness of culinary medicine in core medical school curriculum are limited since this education is typically offered only on an elective basis.

We will describe the process of obtaining approval for culinary medicine in core curriculum and provide outcomes from the inaugural cohort of first- and second-year medical students who completed this training. Culinary medicine education featuring evidence-based nutrition instruction, practical methods to overcome barriers to healthy eating, and a focus on evidence and cooking of paleolithic and vegan diets was piloted in to academic year as a noncredit elective among medical students at the University of Maryland School of Medicine.

Student advocacy, positive course reviews, and improvements in nutrition knowledge, skills, and attitudes compelled medical student education leadership to include a culinary medicine session in core first- and second-year medical student curriculum beginning in Fall The session included evidence supporting numerous popular diets with a focus on practical implementation and cooking of Mediterranean diets.

All medical students in the to first-year class, and most students in the second-year class have completed the culinary medicine training, with the remaining students completing training by January Statistically significant improvements were noted in all nutrition knowledge and patient counseling outcomes assessed. A single session of culinary medicine including evidence on numerous popular diets and experiential cooking instruction is feasible in core medical student curriculum, well-received by students, and offers improvements in nutrition knowledge and confidence in nutrition counseling.

Contact: Isabella Lai, isabellangalai gmail. Shared medical appointments SMAs offer an innovative method to provide education while increasing physician face-time with patients. Covered by third-party payers, our SMAs model promotes optimal self-care through educating patients about East-West nutrition, culinary skills, and mindfulness.

Here, we present data from our pilot study to assess feasibility and patient satisfaction of this particular model. The session centered on educating patients about East-West culinary medicine, integrating Western and Eastern healing food traditions. Each SMA occurred over 90 minutes and included a lecture, cooking demonstration, mindfulness practice, and group discussion. Fifty patients attended the East-West culinary medicine SMAs, in one of the following subject matters: weight management, inflammation, or cancer.

The pilot consisted of 6 individual classes and occurred over a 6-month period. Patients were surveyed after their visit. One hundred percent of patients stated that they would like to expand the informational session into a series. Five patients stated in the comments that they thoroughly enjoyed group discussions and learning about lifestyle modifications from peers. One patient suggested forming an online forum to share healthy recipe ideas and gain support to make better lifestyle choices.

This pilot demonstrated that East-West culinary medicine SMAs were cost-effective, covered by third-party payers, and improved patients understanding of the role of nutrition on health and wellness. Follow-up studies will be performed to study long-term outcomes of SMAs on weight loss, reducing inflammatory symptoms, and improving quality of life in cancer patients. Financially, SMAs suggest a sustainable and effective approach to integrative medicine.

Contact: Elaine Cheung, elaine-cheung northwestern. Physicians are the frontline of advising patients on nutrition; however, physicians report feeling ill-prepared to counsel patients on nutrition. We administered a follow-up survey to previous students who participated in the CUH elective to examine whether these improvements were sustained over time.

In Fall , we administered a follow-up survey to 2 previous cohorts of medical students who participated in the CUH elective to examine the durability of effects over time. Future research should identify potential barriers to healthful cooking and eating in medical training that may interfere with sustained healthful behavior change.

Ultimately, this research may provide evidence to support widespread integration of the CUH elective into medical education. The aim of this project is to increase the ability of faculty to deliver a culinary medicine and service-learning education program to medical trainees.

In , an academic-community partnership between Northwestern Osher Center and Common Threads led to the development of a unique elective Cooking Up Health in which trainees learn about nutrition and cooking and then go into underserved communities to teach elementary school children about healthy habits.

Previously reported data show that participants note increased confidence in and attitudes toward nutrition and obesity counseling. Requests from other sites led to our creation of a training through which attendees can bring culinary medicine to their home institution. By sharing this work, we believe we can impact on the nutrition-competence of future health-care providers, the wellness of students during their training, and improve the health of children and families in communities.

Our goal was to provide other institutions access to a well-researched and vetted course and the tools needed to maximize likelihood of successful implementation. To see whether this was feasible, we hosted workshops in 13 faculty from 8 institutions and 12 faculty from 7 institutions. Workshops were cocurated and taught by academic and community partners. The agenda consisted of participation in a mock culinary medicine class including hands-on cooking, interactive activities, and brainstorming steps to completion.

Postworkshop evaluations showed participants gained confidence in ability to implement the elective and high likelihood of recommending the course and the training. Perceived barriers to success were financial resources and time in the curriculum. It is feasible to use a Train-the Trainer model to disseminate culinary medicine education content.

Additional follow-up is needed to assess success of implementation efforts. Contact: Eric Roseen, Eric. Roseen BMC. Nonpharmacologic treatments are recommended by clinical practice guidelines for low back pain LBP and randomized trials support their effectiveness. However, studies on whether nonpharmacologic treatments are effective when implemented in real-world multi-disciplinary clinical settings are needed.

We analyzed data from the Patients Receiving Integrative Medicine Interventions Effectiveness Registry, a prospective longitudinal study embedded in a practice-based research network. With the widely used, validated PROMIS, we evaluated changes in pain intensity, pain interference, and physical function. We used linear mixed-effects models with a random intercept to account for repeated measures to 1 assess 2- and month PROMIS changes from baseline and 2 whether change over 1 year varied by cumulative dose quartiles, characterized as: none 0 visits , low 1—4 visits , moderate 5—15 visits , or high 15—82 visits.

From August to November , participants were enrolled from 17 clinical sites. Participants with LBP who received 1 to 15 nonpharmacologic visits experienced modest improvements in pain and function over 1 year. This study was a prospective, nonrandomized, open-label clinical trial.

All instruments were administered electronically and separately from trial visits. All forty-four participants completed the trial without any moderate or serious adverse events. Exploratory analyses revealed statistically significant parallel changes in all measures of pain intensity and pain interference, as measured by BPI and the PROMIS subscales.

Oral supplements with resolvins may improve quality of life, reduce pain intensity and interference, and improve mood within 4 weeks in people with chronic pain. The biologic plausibility, consistency between outcomes, and the magnitude of the results of this trial support the need for placebo-controlled clinical trials of oral resolvins. Contact: Theo Slomoff, theo. While there is strong evidence to support the use of multimodal integrative chronic pain management, programs providing this service can be particularly complex to implement in resource-limited settings.

IPMP is a week core program that provides pain education, movement, and tools for pain self-management with optional additional sessions of acupuncture and massage. We used mixed linear models to compare IPMP participants who received acupuncture and massage treatments during the program with those that did not. Data were collected for patients with initial surveys, 75 patients at the end of the study period and 28 patients at the 3-month follow-up. Although there were decreased scores for depression, anxiety, and sleep disturbance, they did not meet our threshold for clinical significance.

No significant improvements were observed for global physical health, physical functioning, or social satisfaction among patients who attended acupuncture and massage sessions. While the core integrative pain management program provided benefit to patients in an underserved setting, participation in additional acupuncture and massage sessions was associated with improvement in the domains of pain catastrophizing, pain interference, and self-efficacy.

Contact: Stephen Dombrowski, dombros ccf. To evaluate the effectiveness of a multidisciplinary, nonpharmacological, integrative approach using shared medical appointments SMAs to reduce opioid use and improve health-related quality-of-life in patients with chronic, non-cancer pain. All participants were referred to the program by their primary care physician, and each cohort was limited to 10 patients. Contact: Elizabeth Sommers, elizabeth.

Chronic pain experienced by children and adolescents represents a significant burden in terms of health, quality of life, and economic costs to U. Team members included a pediatrician, child psychologist, physical therapist, acupuncturist, and massage therapist. Children were referred to the pain clinic from primary care and specialty services within BMC, which is the largest safety-net hospital in the northeastern U.

For this observational assessment, consent and assent were obtained from parents and pediatric patients. Individualized treatment plans were recommended by the IM team. Self-reported survey and electronic medical record data were collected about socioeconomic demographics, pain, use of medical and IM services, and quality of life. We compared health and quality of life indicators and costs of care for each participant from the year before entering our study with these same indicators for the subsequent year.

Eighty-three participants were enrolled. Eighty percent of the group were females. Major economic drivers of cost were Emergency Department ED visits, in-patient hospitalizations, and consultations with medical specialists. No adverse events were reported by any of the participants. Our experience demonstrated that the use of IM approaches in an interdisciplinary team approach is safe, feasible, and acceptable to families. Contact: Jeffery Dusek, jeffery. PRIMIER was designed to collect patient-reported outcome measures PROMs at specified time periods to examine 1 if specific clinical populations eg, chronic pain and 2 IM interventions are associated with improved outcomes over time.

Significant reductions were observed at 12 months on all 7 PROMIS subscales and across all 4 time periods except Physical Functioning at 2 and 4-months. Further hierarchical clustering analyses including heatmaps will provide insights as to whether timing and dose of specific IM interventions and combinations are associated with larger improved outcomes in the chronic pain cohort. National guidelines advise clinicians to decrease opioids for chronic pain management in favor of nonpharmacological modalities, yet we lack evidence for effective strategies.

We evaluated the effectiveness of the IPT model to decrease opioid use and risk. Veterans were assessed prospectively from baseline to 3 and 6 months for change in opioid dose and risk. An adjusted mixed-effects linear regression showed significant average treatment effects of the IPT and time interaction.

This was independent of race, baseline pain severity, opioid use disorder, and other factors. Interdisciplinary models that promote a multimodal approach to pain care, including complementary and integrative health, can lead to sustained reductions in opioid use and risk. Contact: Raveendhara Bannuru, rbannuru tuftsmedicalcenter. Knee osteoarthritis OA is a major public health problem and a leading cause of long-term pain and disability with substantial health-care costs.

No effective medical treatments for the disease currently exist. However, no studies have directly compared mind—body interventions with standard therapies for knee OA using an individual-participant data network meta-analysis approach. This is the first study to examine the efficacy of mind—body therapies for knee OA using this approach, which estimates relative effects of all treatments against each other.

Primary outcomes were pain 0— and function 0— , as measured by the Western Ontario and McMaster Universities Osteoarthritis Index. We synthesized individual participant data and performed a 2-stage analysis using an extension of multivariable Bayesian hierarchical random effects models for multiple treatment comparisons. Tai Chi was as effective as Exercise mean difference: 0. Yoga achieved pain relief comparable to Exercise For function, Tai Chi was as effective as Exercise 1. Yoga had higher benefits on function compared to Exercise 9.

Mind—body interventions produced beneficial effects similar to those of standard physical therapy and exercise in the treatment of knee OA. Therefore, standardized mind—body interventions should be considered as effective therapeutic options for knee OA, highlighting the importance of holistic well-being of the individuals.

Contact: Adam Hanley, adam. This study examined the effect of 3 different adjunctive interventions mindfulness meditation, hypnotic suggestion, and cognitive-behavioral psychoeducation on preoperative pain and anxiety as well as physical function in early recovery following primary TJA. This was a 3-arm, prospective randomized controlled trial conducted in a university-based orthopedic practice. A brief survey measured pain-at-rest, desire for pain medication, and anxiety immediately before and 15 minutes after the preoperative intervention.

Findings from this study suggest that a single minute, mindfulness, or hypnosis intervention immediately reduced preoperative pain intensity, pain unpleasantness, and anxiety in patients preparing for TJA. Historically, we have found no significant improvement in PROMIS PF scores 6 weeks after TJA, whereas with preoperative mindfulness training, we found clinically and statistically significant improvement in self-reported physical function 6 weeks after surgery.

These findings suggest that brief, preoperative mindfulness training may be an effective adjunct that can be easily disseminated in clinical settings, provide immediate preoperative pain and anxiety relief, and may improve postoperative physical functioning. Isabel Roth 1 , and Joan Engebretson 2. With the co-occurring opioid and chronic pain epidemics bringing focus to the need for nonpharmacological pain management, there is a pressing need to develop and implement Integrative Pain Management IPM models.

IPM brings together professionals who are typically underrepresented in biomedical health-care settings: acupuncturists, mindfulness-based stress reduction teachers, and music therapists, among others. Many of these IPM modalities are not currently covered under health insurance, one of several reasons that garnering administrative buy-in to support hiring and credentialing IPM providers may be challenging. An ethnography was conducted in the spring of at a large urban pediatric hospital in the southern United States where an IPM consult service was being pilot tested.

In the current analysis, we aimed to identify implementation strategies used to overcome barriers to implementation of IPM services. TI data management software. Detailed methods have been reported elsewhere. Of the 6 members of the IPM service, 5 had dual training in both a complementary therapy and a biomedical profession.

Working with development professionals to build philanthropic support for the IPM service was crucial to getting the pilot off the ground. To garner administrative buy-in, clinicians worked with high-profile patients offered complementary therapies to their supervisors, built mentoring relationships, and leveraged their non-IPM clinical work to gather support for IPM.

The current analysis identified implementation strategies that may be tested and replicated in future implementation studies of IPM. Identifying effective implementation strategies will be crucial to future IPM implementation efforts. Contact: Els Peeters, e.

There is an increasing demand for complementary and integrative medicine CIM in adults and children in the Netherlands. In , the first Integrative Medicine Pediatrics Outpatient Clinic was created in a large teaching hospital in the Hague. The integrative approach addressing a wide range of neurological complaints among pediatric patients is transforming health care.

The collaboration with CIM therapists by implementation a network of referrals is described. The purpose of this study was 1 to characterize the children and parents making use of the pediatric neurology clinic and 2 to determine the perceived effectiveness of CIM in these children using a referral circuit of CIM therapists. Caregivers and patients experience with CIM treatments were evaluated.

The mean age of the neurology patients was A majority of the families reported benefits from CIM and appreciate the collaboration with the referral circuit. Pediatric neurologists should initiate discussion on CIM helping patients and parents to make informed decisions about using CIM and ameliorating the well-being of these children. Further studies should address the specific role of CIM in children with neurological disorders. Contact: Dennis Anheyer, d.

Increasing demands on teachers and students lead to an increase of distress on both sides. Studies have shown positive effects of mindfulness-based interventions on, for example, executive functioning. The aim of this cluster-randomized trial was to gain more insight in the efficacy of a mindfulness-based training in primary schools. A total of children from 13 primary schools were cluster-randomized either to participate in the program immediately or to wait for half a school year. Afterward, teachers integrated mindfulness techniques in their daily school routine.

Also no significant difference in the health-related quality of life index score was found. However, this difference did not sustain long term. Due to nonsignificant group differences at the other time points measured, it can be concluded that the integration of mindfulness exercises in the classroom does not contribute much to the already existing effects. However, the compliance of the teachers plays a decisive role. Contact: Tiffany Silliman Cohen, sillimanct email. Nonpharmacological-based pain therapies including massage therapy MT and physical therapy PT are an important component of integrative care models for pediatric cancer patients.

The objective is to integrate MT and PT with standard treatment in order to improve function, reduce pain, and alleviate stress in pediatric cancer patients. In September , a pilot initiative offering MT half a day a week in the outpatient pediatric oncology clinic was implemented.

Through multidisciplinary collaborations particularly with nursing and PT, the certified pediatric MT determined patients who would benefit from both therapies to optimize pain control, muscle strength, balance, and physical functioning. Massage interventions included massage, caregiver education, and instruction on self-massage. Follow-up encounters included assessment of symptoms, reinforcement of techniques, and need for additional support.

I look forward to them. Many of our patients are in clinic for multiple hours … it has been extremely easy to incorporate massage therapy into this structure. This pilot has shown that it is feasible and beneficial to add pediatric MT into an outpatient oncology clinic. Integrating a complementary therapy such as MT with PT can help to improve pain, stress, and tight muscles. In addition, it is well received by patients, families and medical team. Increased lower extremity muscle cocontraction may contribute to age-related impairments in gait and postural control.

Tai Chi TC exercise has been shown to improve balance and reduce falls in older adults; however, the neuromuscular mechanisms underlying these benefits are not well understood. This study evaluated the impact of both long- and short-term TC training on lower limb muscle cocontraction and gait characteristics during both single-task ST and cognitively-distracted dual-task DT overground walking.

Long-term effects of TC training were assessed via cross-sectional comparisons of adult TC-experts average Short-term training impact was assessed by randomly assigning TC-naive adults to a 6-month TC training program or a wait-list usual care UC control. Stride time was calculated from footswitch sensors.

CCI was calculated for both walking tasks. Twenty-six TC-experts and 60 TC-naive adults were recruited. Long-term, but not short-term TC training was associated with improved lower extremity neuromuscular coordination. Contact: Gunes Sevinc, gsevinc mgh.

Mindfulness-based interventions have been widely utilized to ameliorate anxiety and stress-related symptoms; however, the neural mechanisms underlying these improvements are still largely unknown. Mindfulness meditation provides a basis for enhanced attentional skills and nonjudgmental awareness of sensory experience.

Here, we propose that the changes in these attentional and sensory systems may modify context-based stimulus-response associations, and that these changes may underlie improvements in anxiety and stress-related symptoms following mindfulness-based interventions. We tested this hypothesis using a well-established contextual fear-learning protocol and a randomized longitudinal study design.

Behavioral changes and alterations in neural activation patterns associated with fear learning from pre- to postinterventions were assessed using functional magnetic resonance imaging. A comparison of self-report measures demonstrated that while both interventions decreased stress levels, MBSR resulted in further improvements in anxiety and emotion regulation. Critically, compared to the SME, MBSR intervention was associated with significant increases in connectivity between the amygdala and primary sensory cortex during fear learning.

Moreover, while SME was associated with enhanced BOLD response in superior frontal cortex, MBSR was associated with enhanced activity in posterior insula, as well as in primary visual cortices during associative learning. These results indicate that mindfulness training may improve anxiety related symptoms predominantly though alterations in context-based stimulus-response associations of the threat-related stimuli. While stress-management education predominantly leads to changes in top-down modulation of threat, MBSR intervention resulted in neuroplastic changes in sensory association areas during associative learning.

Considering that alterations in threat processing have been implicated in the etiology of anxiety and stress-related symptoms, these alterations during associative learning may be a key mechanism through which mindfulness-based interventions alter fear learning and foster stress resilience. Roughly 5 million patients in the United States suffer from paralysis resulting in impaired mobility and communication challenges that significantly impact quality of life.

Through noninvasively decoding user intent in real-time, brain computer interfaces BCIs; devices that establish a direct connection between brains and computers hold the potential to bypass neuromuscular pathways and restore mobility and communication. One promising approach attempts to decipher motor imagery from the electroencephalogram by recording sensorimotor rhythms, which predictably change in response to real and imagined movements.

However, major challenges such as long training times and variable proficiency prevent the widespread clinical adoption of this technology. The dose-dependent response of this effect in the MBSR group suggests the recorded patterns are related to meditation practice, however the strongest patterns of alpha upregulation were observed after BCI training.

Whether this finding is a direct result of mindfulness practice or represents some interaction between meditation and BCI training could be explored by examining the effects of neurofeedback on traditional mindfulness training. The strategy of cultivating meditative states during BCI control through MBSR training could have major clinical implications including better BCI performance, the design of more advanced BCI systems, improved functional health status, and higher quality of life.

Clinical research has shown the benefit of meditation techniques to help reduce symptoms of stress. We explored how expert mediators EMs differ from nonmediators NMs in their response to acute stress. Of the 42 people recruited, 6 subjects were removed due to incomplete data or ineligibility. In total, 16 NM and 20 EM were included in this analysis. Subjects had a median age of 40 20—72 years with 17 females. EM generally had a lower HR throughout the study EMs demonstrate smaller changes in both subjective and objective measures of stress during and after the TSST.

These data support the benefits of meditation to reduce the effects of stress for patients. A secondary analysis was performed to evaluate whether intake of an herbal-mineral supplement that is frequently recommended by integrative medicine providers was associated with categorical shifts in blood pressure BP classification, according to consensus guidelines.

The primary study was designed to prospectively evaluate the safety of the supplement over a 6-month time frame. The investigated supplement contained Rosa centifolia , Boerhaavia diffusa , Dendrogyra cylindrus , Convolvulus pluricaulis , Terminalia arjuna , Tribulus terrestris , Rauwolfia serpentina , Rosa vinca , and magnesium aspartate.

A Wilcoxon signed-rank test was used to evaluate the significance of differences in BP classification between the 3 time points. Mean systolic BP decreased by At the 3-month and 6-month study visits, the percentage of participants categorized as normotensive increased and those categorized as hypertensive decreased compared to baseline. Intake of the herbal-mineral supplement was associated with statistically significant and clinically relevant improvements in BP classification.

These findings may serve to inform health-care providers who recommend this formula to their patients and further justify additional research on the studied formula. Cannabidiol CBD has catapulted to the top of the most-favored cannabinoid charts without data from controlled clinical trials to support its use. This survey was designed to assess who was using CBD-dominant cannabis products, what product type they were using, frequency of use, for what conditions and the perception of its effectiveness.

Patients at 3 integrative medicine clinics and clients of 10 partner dispensaries in San Diego, San Francisco, and Chicago who used CBD-dominant products within the past month were recruited to participate in an institutional review board-approved, anonymous online survey REDCap. A total of surveys were completed from June to May The CBD administration forms used were oral tincture Conditions for which CBD was used were chronic pain The impact of CBD on conditions was rated on a 0 not effective to 10 highly effective scale.

The mean ratings for 36 conditions ranged from 6. Information about CBD was obtained from the internet Despite the fact that information about the use of CBD is not emanating from health-care providers, CBD is being used for a wide range of conditions with self-report of therapeutic benefit as assessed by this 1-time observational survey.

The use of natural health products NHPs is common in North America, with many consumers believing they are safe despite the potential for drug interaction. In the adjusted model, physician inquiry about NHP use was most strongly associated with disclosure by patients odds ratio, 5. Contact: Vincent Minichiello, vincent. Over the course of 2 academic years, a hour mindfulness skills-based curriculum Supportive Training for Residents through Education in Mindfulness was facilitated with resident physicians within the departments of family medicine, pediatrics, anesthesiology, and ophthalmology.

Within 2 months posttraining, residents were invited to participate in a voluntary, semistructured phone interview that was subsequently transcribed and deidentified. A team of 6 reviewers independently read the transcripts, identifying themes, and overarching categories.

The reviewers then met to discuss and establish common language regarding these themes. Sixty-nine residents participated in the trainings, and 36 interviews were completed. Although residents received the same mindfulness training and curriculum, many viewed and internalized the training in unique ways. Some residents referred to mindfulness as a tool to be wielded in certain situations, others viewed it as a way to relax and decompress, a method for self-exploration, or as a lens with which to view the world differently.

Residents reported using mindfulness practices most frequently between patient encounters and prior to entering a patient room. These brief practices included mindful walking, deep breathing, and body scan exercises. Residents found these mindfulness practices helped them better cope with patient-related frustrations, be less distracted and more present with each of their patients, and maintain an awareness of their own stress levels and competing emotions.

Across specialties resident physicians found that a hour mindfulness training was influential in their clinical practices. While their perspectives of mindfulness practice varied, residents commonly agreed that they were able to apply brief mindfulness interventions to support themselves and patients in clinic. We conducted a pilot randomized controlled trial RCT to explore whether mindfulness training MT , alone or in combination with aerobic exercise training AT , may improve cognitive function in individuals at risk of dementia.

Retention rates were These results suggest a possible effect of MT on cognitive function in older individuals at risk of dementia. AT did not improve cognitive function and may require a longer intervention duration to show an effect. These promising findings need to be confirmed in a larger RCT. Contact: Erica Sibinga, esibinga jhmi.

We have found that mindfulness-based stress reduction MBSR for urban youth improves psychological functioning and decreases trauma symptoms. Linear additive modeling was used to compared study arms, accounting for baseline differences. Ninety-seven year-old participants consented and 74 completed baseline data collection and were randomized to MBSR or HT.

Given the significant vulnerability of this population and the importance of achieving higher rates of HIV viral suppression to reduce transmission, MBSR remains a promising approach to enhance treatment of HIV-infected youth in effort to end the HIV epidemic. Contact: Rebecca Wells, rewells wakehealth. Secondary outcomes: changes in disability, self-efficacy, pain catastrophizing, and depression. No adverse events or side effects were reported. Contact: Holger Cramer, h. The aim of this study was to assess the efficacy and safety of a comprehensive mind—body medicine program for lifestyle modification including a fasting period in patients with the metabolic syndrome compared to a standard lifestyle program.

One hundred forty-five patients with the metabolic syndrome CLM included an initial 5-day fasting intervention followed by 10 weekly 6-hour group meetings focusing on nutrition, aerobic exercise, mindfulness, yoga, and cognitive restructuring. Secondary outcomes included anthropometric, laboratory, and self-report measures.

Outcomes were assessed at weeks 1 after the fasting week , 12 after the lifestyle programs , and 24 follow-up. Few significant group differences were found at week 12 and No serious adverse events occurred. Fasting induced positive short-term effects in patients with the metabolic syndrome; however, these effects were not maintained in the longer term.

Fasting can thus be considered a treatment option for this patient group, although it remains to be investigated whether and how the effects of fasting can be maintained in the longer term. Contact: Paul G. Werthmann, paul. Viscum album extracts VAE have been intensively investigated preclinically and clinically, particularly with regard to antitumoral activity, immunomodulation, quality of live, survival, and safety.

Doctors with high experience in VAE therapy describe treatment regimens and clinically significant outcomes not reported in published studies of VAE. We asked doctors for cases of VAE therapy in cancer patients which they regarded to show a clinically significant outcome connected to VAE therapy. The recruitment strategy included requests via e-mail lists and meetings as well as contacts from a qualitative study with expert doctors in VAE therapy.

We assessed the cases for relevance clinically significant outcome in comparison with the literature and ran them through a validation process: check for data completeness; triangulation of the data from different sources; reevaluation of crucial diagnostic and follow-up tests; and discussion with experts. A total of cases were recruited; 91 cases were excluded in the assessment process, mainly for relevance and validity; 9 cases were published in peer-reviewed medical journals; and 11 are still being investigated.

Older patient data often were incomplete and made validation impossible. The published case reports cover the tumor sites: skin, pancreas, kidney, ovary, pleura, skull, and lymphatic tissue. VAE was administered subcutaneously, intravenously, and intralesionally. In some of the cases, unusually high dosages of VAE were used.

Outcomes were long-term survival, tumor regression, improvement of quality of life, and reduced side effects from cancer treatment. Significant clinical observations of VAE therapy could be captured, elaborated scientifically, and published as case reports in peer-reviewed medical journals. Our search and elaboration procedure could be a model of how to capture relevant clinical experience.

Contact: Janet Nguyen, jngu uni. Interprofessional communication IPC between health-care practitioners HCP can optimise the safe delivery of patient-centred care. In response to calls from HCP, the Australasian Integrative Medicine Association AIMA established an interdisciplinary working group to develop an IPC Guiding Principles for Letter Writing that included letter templates for medical practitioners, pharmacists, nurses, allied health and complementary medicine practitioners. Development included stakeholder consultation on the draft document.

A mixed-methods study design was used to analyse the results from an online public consultation survey and paper questionnaires from AIMA IPC workshop participants. Quantitative and qualitative data from the 2 datasets were merged utilising the principles of triangulation to identify meta-themes.

The respondents 64 from the public consultation survey and 53 workshop participants were representative of the Australian health-care sectors and the lay community. The key themes relating to IPC were the importance of continuity of care, clarity of communication, professionalism, and ongoing education. Results from the 2 samples were congruent with no significant statistical nor qualitative differences identified.

Feedback from respondents will be used to revise the document prior to AIMA endorsement. The findings highlight the role of formal communication pathways in providing multidisciplinary care that is safe, coordinated, and patient centred, and the need for further IPC training and education. Contact: Mary Koithan, mkoithan arizona. A transformed high-quality health-care system requires that nursing faculty and academic leaders be prepared to transform nursing education to prepare our workforce.

Transforming care requires faculty proficient in developing, implementing, and evaluating curricula based on the concepts and principles of integrative care delivery. L Susan Wieland 1 , and Joel Gagnier 2. Contact: L. Susan Wieland, lswieland gmail. Cochrane systematic reviews are considered the gold standard for evaluating the evidence on interventions.

A core component of Cochrane methodology is the Cochrane risk of bias tool RoB 1. In , RoB 1. It is important to evaluate how RoB 2. RoB 2. We assessed the criteria and rating instructions for each bias domain and considered whether these had changed since RoB 1. Criteria for performance bias and detection bias in unblinded trials have changed.

Unblinded trials are no longer automatically rated at high risk of performance bias, but subjective outcomes eg, pain in unblinded trials are now automatically at high risk of detection bias, even if obtained through a blinded assessor. New RoB 2. According to RoB 2. We question the appropriateness and utility of these judgments, particularly in pragmatic trials, which should not be blinded. We suggest some alternative approaches to assessing the risk of detection bias for these outcomes and propose collaboration to develop recommendations on this topic.

Along the lines of the Precision Medicine Model, the purpose of this presentation is to describe the 2-phase content validation process used for a taxonomy of skills learned from mindfulness practice that will allow more targeted interventions to address skill-deficits in defined clinical conditions. Phase I development utilized 11 subject matter experts SMEs over 5 months. I-CVIs ranged from 0. In the last decade, network meta-analysis NMA has become a well-established knowledge synthesis technique used in systematic reviews SR to compare multiple treatments based on all available direct and indirect evidence.

Its extent of use to compare therapies in the realm of complementary medicine CAM intervention has not been assessed. An information specialist executed a multidatabase search, and 2 reviewers performed study selection and data collection. Information on publication characteristics, diseases studied, interventions compared, reporting transparency, outcomes assessed, and other parameters were extracted from each review.

Reviews were published between and , with the majority published between and Dietary supplements A diverse set of conditions was identified, the most common being various forms of cancer Most reviews adequately addressed a majority of the PRISMA NMA extension items; however, there were limitations in indication of an existing review protocol, methods to explore network geometry and related findings , and exploration of risk of bias across studies such as publication bias.

Contact: L Susan Wieland, lswieland gmail. The systematic review evidence for effective mind—body therapies for chronic pain is fragmentary and dissemination of information from existing reviews could be improved. We developed and tested a survey with the CAM Field Advisory Board in and then disseminated a revised and expanded online questionnaire through a range of social media channels in We collected demographics and desires for more information on topics surrounding 6 chronic pain conditions eg, chronic back pain and 12 mind—body therapies eg, mindfulness defined by our funder.

Relevant Cochrane acupuncture reviews were published between and and updates of and reviews are ongoing. There is 1 relevant Cochrane yoga review being updated and 1 at protocol stage. Only 1 relevant Cochrane review exists for mindfulness or for massage. The CAM Field is working with Cochrane review groups to produce or update reviews, developing strategies to disseminate the results of these reviews when completed, and looking at how best to use non-Cochrane evidence in the meantime.

Active stretching targeting connective tissues is integral to mind—body therapies including yoga and Tai Chi. These therapies show promise in relieving musculoskeletal pain, but the biological mechanisms underlying therapeutic effects remain largely unknown. We have previously studied the impact of active stretching on inflammatory processes in a rat model. Here, we extend this work to a porcine model which closer resembles the human musculoskeletal system.

We tested the feasibility of an active stretching paradigm in pigs and report preliminary findings on the impact of stretching on local tissue inflammation by measuring inflammatory lesion size, granulocyte and macrophage infiltration, and systemic inflammatory markers.

Lesion area was measured in situ with calipers and cells harvested and stained with CD, granulocyte, and CD mAbs. Active stretching was well tolerated. On average, S lesions contained fewer granulocytes and macrophages than the NS group.

A porcine model shows promise for studying the impact of active stretching on inflammation and musculoskeletal health. Future studies with larger samples and higher stretching doses are warranted. Contact: EunMee Yang, eunmeeyang gmail. Excessive inflammation in myocardial infarction MI is associated with exacerbated myocardial injury. Attenuating inflammation has been proposed as a potential strategy for improving myocardial repair in MI.

In previous studies, electroacupuncture EA has been shown to moderate inflammation and exert beneficial effects in various heart-related conditions, but its efficacy and immune-modulating effects on MI are unclear.

Infarcted rats treated with EA showed decreased levels of myocardial enzymes compared to the nontreated infarcted group: cTnT MI: This study demonstrates that EA can attenuate myocardial injury and inflammation in the postinfarcted heart. The findings also provide new insight about the ability of EA to regulate macrophage polarization in MI.

While these findings suggest that acupuncture is cardio-protective, potentially through its immune-modulating effects, more research is needed to better understand the mechanisms and clinical implications of acupuncture for MI. Contact: Joong Sun Kim, centraline kiom. Mantidis Ootheca MO , described as the ootheca of Hierodula patellifera Serville, , Tenodera angustipennis Saussure, , or Statilia maculate Thunberg, in Korean Herbal Pharmacopoeia, is an important herbal material that has been traditionally used for treating several medical conditions including spermatorrhea and pediatric enuresis in Korea.

We evaluated the effect of MO on testicular injury in mouse after radiation exposure. MO protected testicular morphological changes, such as changes in seminiferous epithelial height after radiation exposure. In addition, the remaining proliferating germ cells were higher in the MO-treated group than in the radiation group.

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